Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis

Pulmonary alveolar microlithiasis is an autosomal recessive lung disease caused by a deficiency in the pulmonary epithelial Npt2b sodium-phosphate co-transporter that results in accumulation of phosphate and formation of hydroxyapatite microliths in the alveolar space. The single cell transcriptomic...

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Detalles Bibliográficos
Autores principales: Uehara, Yasuaki, Tanaka, Yusuke, Zhao, Shuyang, Nikolaidis, Nikolaos M., Pitstick, Lori B., Wu, Huixing, Yu, Jane J., Zhang, Erik, Hasegawa, Yoshihiro, Noel, John G., Gardner, Jason C., Kopras, Elizabeth J., Haffey, Wendy D., Greis, Kenneth D., Guo, Jinbang, Woods, Jason C., Wikenheiser-Brokamp, Kathryn A., Kyle, Jennifer E., Ansong, Charles, Teitelbaum, Steven L., Inoue, Yoshikazu, Altinişik, Göksel, Xu, Yan, McCormack, Francis X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981730/
https://www.ncbi.nlm.nih.gov/pubmed/36864068
http://dx.doi.org/10.1038/s41467-023-36810-8

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