Cargando…

Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study

Epigenetics regulates gene expression and has been confirmed to play a critical role in a variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease (NAFLD), osteoporosis, gout, hyperthyroidism, hypothyroidism and others. The term ‘epigenetics’ was firstly proposed i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yan-Lin, Lin, Zheng-Jun, Li, Chang-Chun, Lin, Xiao, Shan, Su-Kang, Guo, Bei, Zheng, Ming-Hui, Li, Fuxingzi, Yuan, Ling-Qing, Li, Zhi-hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981733/ https://www.ncbi.nlm.nih.gov/pubmed/36864020 http://dx.doi.org/10.1038/s41392-023-01333-7

Ejemplares similares

Identifying key genes of classic papillary thyroid cancer in women aged more than 55 years old using bioinformatics analysis
por: Li, Chang-Chun, et al.
Publicado: (2022)

The Suppression of miR-199a-3p by Promoter Methylation Contributes to Papillary Thyroid Carcinoma Aggressiveness by Targeting RAP2a and DNMT3a
por: Wu, Feng, et al.
Publicado: (2020)

New Insights Into Implications of CTRP3 in Obesity, Metabolic Dysfunction, and Cardiovascular Diseases: Potential of Therapeutic Interventions
por: Guo, Bei, et al.
Publicado: (2020)

The Multi-Therapeutic Role of MSCs in Diabetic Nephropathy
por: Wang, Yi, et al.
Publicado: (2021)

Melatonin alleviates vascular calcification and ageing through exosomal miR‐204/miR‐211 cluster in a paracrine manner
por: Xu, Feng, et al.
Publicado: (2020)

Plasma Exosomes Derived From Patients With End-Stage Renal Disease and Renal Transplant Recipients Have Different Effects on Vascular Calcification
por: Lin, Xiao, et al.
Publicado: (2021)

The Role of Substance P in the Regulation of Bone and Cartilage Metabolic Activity
por: Li, Fu-Xing-Zi, et al.
Publicado: (2020)

The Role of Epigenetics in Arterial Calcification
por: Wu, Shan-Shan, et al.
Publicado: (2015)

Exosomes as Mediators of Cell-to-Cell Communication in Thyroid Disease
por: Wang, Yi, et al.
Publicado: (2020)

Aberration methylation of miR-34b was involved in regulating vascular calcification by targeting Notch1
por: Lin, Xiao, et al.
Publicado: (2019)

Exosomes and Obesity-Related Insulin Resistance
por: Lei, Li-Min, et al.
Publicado: (2021)

The Role of Mesenchymal Stromal Cells-Derived Small Extracellular Vesicles in Diabetes and Its Chronic Complications
por: Li, Fu-Xing-Zi, et al.
Publicado: (2021)

Ferroptosis and Its Potential Role in Metabolic Diseases: A Curse or Revitalization?
por: Duan, Jia-Yue, et al.
Publicado: (2021)

Protective role of small extracellular vesicles derived from HUVECs treated with AGEs in diabetic vascular calcification
por: Guo, Bei, et al.
Publicado: (2022)

Epigenetic dynamics and interplay during spermatogenesis and embryogenesis: implications for male fertility and offspring health
por: Ge, Shao-Qin, et al.
Publicado: (2017)

Astragaloside IV for Experimental Focal Cerebral Ischemia: Preclinical Evidence and Possible Mechanisms
por: Wang, Hui-Lin, et al.
Publicado: (2017)

Aberrant DNA methylation of synaptophysin is involved in adrenal cortisol-producing adenoma
por: Zhong, Jia-Yu, et al.
Publicado: (2019)

H19 Promotes Osteoblastic Transition by Acting as ceRNA of miR-140-5p in Vascular Smooth Muscle Cells
por: Xu, Feng, et al.
Publicado: (2022)

The Controversial Role of Irisin in Clinical Management of Coronary Heart Disease
por: Ou-Yang, Wen-Lu, et al.
Publicado: (2021)

Global publication trends and research trends of necroptosis application in tumor: A bibliometric analysis
por: Wu, Yun-Yun, et al.
Publicado: (2023)

Genomic loss of EZH2 leads to epigenetic modifications and overexpression of the HOX gene clusters in myelodysplastic syndrome
por: Xu, Feng, et al.
Publicado: (2016)

A genetic development route analysis on MDS subset carrying initial epigenetic gene mutations
por: Li, Xiao, et al.
Publicado: (2020)

MYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21
por: Liu, Li, et al.
Publicado: (2017)

m6A-regulated tumor glycolysis: new advances in epigenetics and metabolism
por: Yue, Shi-Wei, et al.
Publicado: (2023)

Rhodiola rosea L. Improves Learning and Memory Function: Preclinical Evidence and Possible Mechanisms
por: Ma, Gou-ping, et al.
Publicado: (2018)

Epigenetic Mechanisms in Irritable Bowel Syndrome
por: Mahurkar-Joshi, Swapna, et al.
Publicado: (2020)

Suanzaoren Formulae for Insomnia: Updated Clinical Evidence and Possible Mechanisms
por: Zhou, Qi-Hui, et al.
Publicado: (2018)

Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials
por: Shi, Yuncong, et al.
Publicado: (2022)

The Interplay Between the Renin-Angiotensin-Aldosterone System and Parathyroid Hormone
por: Zheng, Ming-Hui, et al.
Publicado: (2020)

Preclinical Evidence and Possible Mechanisms of Extracts or Compounds from Cistanches for Alzheimer’s Disease
por: Zhou, Xiao-Li, et al.
Publicado: (2019)

Molecular and physiological mechanisms of tea (Camellia sinensis (L.) O. Kuntze) leaf and root in response to nitrogen deficiency
por: Lin, Zheng-He, et al.
Publicado: (2023)

Epigenetics: A Potential Mechanism Involved in the Pathogenesis of Various Adverse Consequences of Obstructive Sleep Apnea
por: Chen, Yung-Che, et al.
Publicado: (2019)

Long Non-coding RNA LINC00628 Interacts Epigenetically with the LAMA3 Promoter and Contributes to Lung Adenocarcinoma
por: Xu, Shu-Feng, et al.
Publicado: (2019)

Correction: Cold exposure protects against medial arterial calcification development via autophagy
por: Li, Fu-Xing-Zi, et al.
Publicado: (2023)

Cold exposure protects against medial arterial calcification development via autophagy
por: Li, Fu-Xing-Zi, et al.
Publicado: (2023)

The GC-TOF/MS-based Metabolomic analysis reveals altered metabolic profiles in nitrogen-deficient leaves and roots of tea plants (Camellia sinensis)
por: Lin, Zheng-He, et al.
Publicado: (2021)

Vascular wall microenvironment: exosomes secreted by adventitial fibroblasts induced vascular calcification
por: Zheng, Ming-Hui, et al.
Publicado: (2023)

Dynamics of epigenetic regulator gene BCOR mutation and response predictive value for hypomethylating agents in patients with myelodysplastic syndrome
por: Li, Xiao, et al.
Publicado: (2021)

Unraveling the Pathogenesis of Asthma and Chronic Obstructive Pulmonary Disease Overlap: Focusing on Epigenetic Mechanisms
por: Chen, Yung-Che, et al.
Publicado: (2022)

Targeting Epigenetic Mechanisms in Vascular Aging
por: Lin, Zhongxiao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a7nanonss60dgikssn3po1b8rh