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Targeted dual base editing with Campylobacter jejuni Cas9 by single AAV-mediated delivery

Various CRISPR‒Cas9 orthologs are used in genome engineering. One of the smallest Cas9 orthologs is cjCas9 derived from Campylobacter jejuni, which is a highly specific genome editing tool. Here, we developed cjCas9-based base editors including a cytosine base editor (cjCBEmax) and an adenine base e...

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Detalles Bibliográficos
Autores principales:	Kweon, Jiyeon, Jang, An-Hee, Kwon, Eunji, Kim, Ungi, Shin, Ha Rim, See, Jieun, Jang, Gayoung, Lee, Chaeyeon, Koo, Taeyoung, Kim, Seokjoong, Kim, Yongsub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981745/ https://www.ncbi.nlm.nih.gov/pubmed/36720917 http://dx.doi.org/10.1038/s12276-023-00938-w

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