Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles

Super-resolution microscopic imaging employing upconversion nanoparticles is applied to reveal the surface heterogeneity of tumor cell-derived small extracellular vesicles, i.e., exosome. The number of surface antigens of every extracellular vesicles can be quantified by both the high imaging resolu...

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Detalles Bibliográficos
Autores principales: Pu, Rui, Zhan, Qiuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981756/
https://www.ncbi.nlm.nih.gov/pubmed/36864025
http://dx.doi.org/10.1038/s41377-023-01106-5
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author Pu, Rui
Zhan, Qiuqiang
author_facet Pu, Rui
Zhan, Qiuqiang
author_sort Pu, Rui
collection PubMed
description Super-resolution microscopic imaging employing upconversion nanoparticles is applied to reveal the surface heterogeneity of tumor cell-derived small extracellular vesicles, i.e., exosome. The number of surface antigens of every extracellular vesicles can be quantified by both the high imaging resolution and stable brightness of upconversion nanoparticles. This method proves its great potential in nanoscale biological studies.
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spelling pubmed-99817562023-03-04 Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles Pu, Rui Zhan, Qiuqiang Light Sci Appl News & Views Super-resolution microscopic imaging employing upconversion nanoparticles is applied to reveal the surface heterogeneity of tumor cell-derived small extracellular vesicles, i.e., exosome. The number of surface antigens of every extracellular vesicles can be quantified by both the high imaging resolution and stable brightness of upconversion nanoparticles. This method proves its great potential in nanoscale biological studies. Nature Publishing Group UK 2023-03-03 /pmc/articles/PMC9981756/ /pubmed/36864025 http://dx.doi.org/10.1038/s41377-023-01106-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle News & Views
Pu, Rui
Zhan, Qiuqiang
Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles
title Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles
title_full Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles
title_fullStr Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles
title_full_unstemmed Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles
title_short Upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles
title_sort upconversion nanoscopy revealing surface heterogeneity of tumor-secreted extracellular vesicles
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981756/
https://www.ncbi.nlm.nih.gov/pubmed/36864025
http://dx.doi.org/10.1038/s41377-023-01106-5
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