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BET inhibitors synergize with sunitinib in melanoma through GDF15 suppression

Targeting bromodomain and extra-terminal domain (BET) proteins has shown a promising therapeutic effect on melanoma. The development of strategies to better kill melanoma cells with BET inhibitor treatment may provide new clinical applications. Here, we used a drug synergy screening approach to comb...

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Detalles Bibliográficos
Autores principales: Zeng, Furong, Li, Yayun, Meng, Yu, Sun, Huiyan, He, Yi, Yin, Mingzhu, Chen, Xiang, Deng, Guangtong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981764/
https://www.ncbi.nlm.nih.gov/pubmed/36720918
http://dx.doi.org/10.1038/s12276-023-00936-y

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