Cargando…

Glycolysis-enhancing α(1)-adrenergic antagonists modify cognitive symptoms related to Parkinson’s disease

Terazosin is an α(1)-adrenergic receptor antagonist that enhances glycolysis and increases cellular ATP by binding to the enzyme phosphoglycerate kinase 1 (PGK1). Recent work has shown that terazosin is protective against motor dysfunction in rodent models of Parkinson’s disease (PD) and is associat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weber, Matthew A., Sivakumar, Kartik, Tabakovic, Ervina E., Oya, Mayu, Aldridge, Georgina M., Zhang, Qiang, Simmering, Jacob E., Narayanan, Nandakumar S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981768/ https://www.ncbi.nlm.nih.gov/pubmed/36864060 http://dx.doi.org/10.1038/s41531-023-00477-1

Ejemplares similares

Use of Glycolysis‐Enhancing Drugs and Risk of Parkinson's Disease
por: Simmering, Jacob E., et al.
Publicado: (2022)

Association of Glycolysis-Enhancing α-1 Blockers With Risk of Developing Parkinson Disease
por: Simmering, Jacob E., et al.
Publicado: (2021)

61 Detecting Parkinson’s Disease Using Computer Vision
por: Simmering, Jacob, et al.
Publicado: (2023)

Parkinson’s Disease Dementia and Dementia with Lewy Bodies Have Similar Neuropsychological Profiles
por: Aldridge, Georgina M., et al.
Publicado: (2018)

Beta adrenergic antagonists and antianginal drugs
por: Stever, Lindsey M., et al.
Publicado: (2021)

Beta-Adrenergic Antagonist Tolerance in Amyloid Cardiomyopathy
por: Ramsell, Stuart, et al.
Publicado: (2022)

Interaction between Antagonist of Cannabinoid Receptor and Antagonist of Adrenergic Receptor on Anxiety in Male Rat
por: Komaki, Alireza, et al.
Publicado: (2014)

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma
por: Wolter, Jennifer K, et al.
Publicado: (2013)

Beta-adrenergic receptor antagonists and chronic heart failure in children
por: Filippo, Sylvie Di
Publicado: (2007)

QSPR analysis of some agonists and antagonists of α-adrenergic receptors
por: Kawczak, Piotr, et al.
Publicado: (2014)

Characterization of β-adrenergic receptors in bovine intramuscular and subcutaneous adipose tissue: comparison of lubabegron fumarate with β-adrenergic receptor agonists and antagonists
por: Hwang, Jinhee H, et al.
Publicado: (2021)

Alpha-synuclein pre-formed fibrils injected into prefrontal cortex primarily spread to cortical and subcortical structures and lead to isolated behavioral symptoms
por: Weber, Matthew A., et al.
Publicado: (2023)

Phase-adaptive brain stimulation of striatal D1 medium spiny neurons in dopamine-depleted mice
por: Kim, Youngcho, et al.
Publicado: (2022)

The Specific α1-Adrenergic Receptor Antagonist Prazosin Influences the Urine Proteome
por: Zhao, Mindi, et al.
Publicado: (2016)

Effects of Adrenergic Agonists and Antagonists on Cardiopulmonary Function During Normobaric Hypoxia in Rat
por: Bölter, Christian, et al.
Publicado: (2019)

Neural signatures of α2-Adrenergic agonist-induced unconsciousness and awakening by antagonist
por: Ballesteros, Jesus Javier, et al.
Publicado: (2020)

β-adrenergic-receptor-antagonists/dexmedetomidine: Recurrent asystole and syncope: case report
Publicado: (2022)

The Alpha-1 Adrenergic Receptor Antagonist Prazosin Reduces Binge-Like Eating in Rats
por: Hicks, Callum, et al.
Publicado: (2020)

Inhibition of VMAT2 by β2-adrenergic agonists, antagonists, and the atypical antipsychotic ziprasidone
por: Støve, Svein Isungset, et al.
Publicado: (2022)

Stimulation of Alpha-1-Adrenergic Receptor Ameliorates Obesity-Induced Cataracts by Activating Glycolysis and Inhibiting Cataract-Inducing Factors
por: Lee, Yong-Jik, et al.
Publicado: (2022)

Beta 2 Adrenergic Receptor Selective Antagonist Enhances Mechanically Stimulated Bone Anabolism in Aged Mice
por: E. Worton, Leah, et al.
Publicado: (2022)

Salience network and cognitive impairment in Parkinson’s disease
por: Yeager, Brooke E, et al.
Publicado: (2023)

NMDA antagonists for treating the non-motor symptoms in Parkinson’s disease
por: Vanle, Brigitte, et al.
Publicado: (2018)

Molecular Modeling Study of Chiral Separation and Recognition Mechanism of β-Adrenergic Antagonists by Capillary Electrophoresis
por: Li, Wuhong, et al.
Publicado: (2012)

Effects of β-adrenergic receptor antagonists on oxidative stress in purified rat retinal ganglion cells
por: Yu, Zi-Kui, et al.
Publicado: (2007)

Effect of Flos carthami Extract and α (1)-Adrenergic Antagonists on the Porcine Proximal Ureteral Peristalsis
por: Wu, San-Yuan, et al.
Publicado: (2014)

The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19
por: Rose, Liam, et al.
Publicado: (2021)

The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality from COVID-19
por: Rose, Liam, et al.
Publicado: (2021)

Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup
por: Bouchard, Josée, et al.
Publicado: (2021)

Bradycardia From a Non-selective Beta-Adrenergic Antagonist, Timolol, Applied Ophthalmologically for Glaucoma
por: May, Gedaliah, et al.
Publicado: (2022)

Effect Of α2-Adrenergic Agonists And Antagonists On Cytokine Release From Human Lung Macrophages Cultured In Vitro
por: Piazza, O., et al.
Publicado: (2016)

Executive dysfunction in Parkinson’s disease and timing deficits
por: Parker, Krystal L., et al.
Publicado: (2013)

Does Black vs. White race affect practitioners’ appraisal of Parkinson’s disease?
por: Harris, Shana, et al.
Publicado: (2023)

Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures
por: Vinik, Aaron I., et al.
Publicado: (2014)

The beta adrenergic receptor antagonist propranolol alters mitogenic and apoptotic signaling in late stage breast cancer
por: Montoya, Alexa, et al.
Publicado: (2019)

Effects of β-Adrenergic Antagonists on Chemoradiation Therapy for Locally Advanced Non-Small Cell Lung Cancer
por: Chaudhary, Kunal R., et al.
Publicado: (2019)

Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection
por: Koenecke, Allison, et al.
Publicado: (2021)

PSUN11 Outcomes of Nonselective or Selective Alpha-Adrenergic Antagonist for Preoperative Management of Intra-adrenal Pheochromocytoma
por: Heckart, Jonathan, et al.
Publicado: (2022)

Meta-analysis of the efficacy and adverse drug reactions of adrenergic alpha-antagonists in treating children with ureteral calculi
por: Sun, Kai, et al.
Publicado: (2023)

BAY-6096: A Potent, Selective, and Highly Water-Soluble Adrenergic α(2B) Antagonist
por: Meibom, Daniel, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_opkoiltl7bc2l0jk3p62jhqii9