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Signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system
Diabetes is a chronic noncommunicable disease, which is related to lifestyle, environmental and other factors. The main disease of diabetes is the pancreas. Inflammation, oxidative stress and other factors can interfere with the conduction of various cell signaling pathways, thus inducing pancreatic...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981801/ https://www.ncbi.nlm.nih.gov/pubmed/36873938 http://dx.doi.org/10.3389/fgene.2023.1119181 |
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author | Song, Ge Zhang, Yiqian Jiang, Yihua Zhang, Huan Gu, Wen Xu, Xiu Yao, Jing Chen, Zhengfang |
author_facet | Song, Ge Zhang, Yiqian Jiang, Yihua Zhang, Huan Gu, Wen Xu, Xiu Yao, Jing Chen, Zhengfang |
author_sort | Song, Ge |
collection | PubMed |
description | Diabetes is a chronic noncommunicable disease, which is related to lifestyle, environmental and other factors. The main disease of diabetes is the pancreas. Inflammation, oxidative stress and other factors can interfere with the conduction of various cell signaling pathways, thus inducing pancreatic tissue lesions and diabetes. Precision medicine covers epidemiology, preventive medicine, rehabilitation medicine and clinical medicine. On the basis of precision medicine big data analysis, this paper takes pancreas as the target to analyze the signal pathway of diabetes treatment. This paper analyzes from the five aspects of the age structure of diabetes, the blood sugar control standard of type 2 elderly diabetes mellitus, the changes in the number of diabetic patients, the ratio of patients using pancreatic species and the changes in blood sugar using the pancreas. The results of the study showed that targeted pancreatic therapy for diabetes reduced the diabetic blood glucose rate by approximately 6.94%. |
format | Online Article Text |
id | pubmed-9981801 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99818012023-03-04 Signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system Song, Ge Zhang, Yiqian Jiang, Yihua Zhang, Huan Gu, Wen Xu, Xiu Yao, Jing Chen, Zhengfang Front Genet Genetics Diabetes is a chronic noncommunicable disease, which is related to lifestyle, environmental and other factors. The main disease of diabetes is the pancreas. Inflammation, oxidative stress and other factors can interfere with the conduction of various cell signaling pathways, thus inducing pancreatic tissue lesions and diabetes. Precision medicine covers epidemiology, preventive medicine, rehabilitation medicine and clinical medicine. On the basis of precision medicine big data analysis, this paper takes pancreas as the target to analyze the signal pathway of diabetes treatment. This paper analyzes from the five aspects of the age structure of diabetes, the blood sugar control standard of type 2 elderly diabetes mellitus, the changes in the number of diabetic patients, the ratio of patients using pancreatic species and the changes in blood sugar using the pancreas. The results of the study showed that targeted pancreatic therapy for diabetes reduced the diabetic blood glucose rate by approximately 6.94%. Frontiers Media S.A. 2023-02-17 /pmc/articles/PMC9981801/ /pubmed/36873938 http://dx.doi.org/10.3389/fgene.2023.1119181 Text en Copyright © 2023 Song, Zhang, Jiang, Zhang, Gu, Xu, Yao and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics Song, Ge Zhang, Yiqian Jiang, Yihua Zhang, Huan Gu, Wen Xu, Xiu Yao, Jing Chen, Zhengfang Signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system |
title | Signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system |
title_full | Signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system |
title_fullStr | Signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system |
title_full_unstemmed | Signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system |
title_short | Signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system |
title_sort | signaling pathway of targeting the pancreas in the treatment of diabetes under the precision medicine big data evaluation system |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981801/ https://www.ncbi.nlm.nih.gov/pubmed/36873938 http://dx.doi.org/10.3389/fgene.2023.1119181 |
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