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Cumulative Laxation Response with Methylnaltrexone: Implications for Hospitalized Patients with Advanced Illness and Opioid-Induced Constipation
BACKGROUND: Opioid-induced constipation (OIC) may increase the risk of fecal impaction and mortality in patients with advanced illness. Methylnaltrexone (MNTX) is efficacious for OIC. OBJECTIVE: The purpose of this analysis was to evaluate cumulative rescue-free laxation response with repeat MNTX do...
Autores principales: | Farchadi, David, Slatkin, Neal E., Stambler, Nancy, Israel, Robert J., Matus, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981808/ https://www.ncbi.nlm.nih.gov/pubmed/36875317 http://dx.doi.org/10.1016/j.curtheres.2023.100694 |
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