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Bone Marrow Mesenchymal Stem Cells-Derived miR-21-5p Protects Grafted Islets Against Apoptosis by Targeting PDCD4

The apoptosis of grafted islets is an urgent problem due to the high rate of islet loss soon after transplantation. MicroRNA-21-5p (miR-21-5p) is an essential mediator of bone marrow mesenchymal stem cells-derived exosomes (BMSCs-Exo) during anti-apoptosis, but its effect and the underlying molecula...

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Detalles Bibliográficos
Autores principales: Wang, Jingwen, Wang, Jiale, Wang, Ying, Ma, Ruiyang, Zhang, Shucong, Zheng, Jin, Xue, Wujun, Ding, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982070/
https://www.ncbi.nlm.nih.gov/pubmed/36512434
http://dx.doi.org/10.1093/stmcls/sxac085

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