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Targeting SELPLG/P‐selectin glycoprotein ligand 1 in preclinical ARDS: Genetic and epigenetic regulation of the SELPLG promoter

We previously identified a missense single nucleotide polymorphism rs2228315 (G>A, Met62Ile) in the selectin‐P‐ligand gene (SELPLG), encoding P‐selectin glycoprotein ligand 1 (PSGL‐1), to be associated with increased susceptibility to acute respiratory distress syndrome (ARDS). These earlier stud...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoguang, Sammani, Saad, Hufford, Matthew, Sun, Belinda L., Kempf, Carrie L., Camp, Sara M., Garcia, Joe G. N., Bime, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982077/
https://www.ncbi.nlm.nih.gov/pubmed/36873461
http://dx.doi.org/10.1002/pul2.12206