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Primary breast angiosarcoma: A case report

BACKGROUND: Primary breast angiosarcoma (PBA) is a rare sarcoma, accounting for only 0.04% of all breast malignancies, with a difficult diagnosis and a poor prognosis. Mastectomy is the standard treatment, and the role of adjuvant treatment (chemotherapy and/or radiotherapy following surgery) remain...

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Autores principales: He, Yu, Qian, Liyuan, Chen, Lang, Liu, Yang, Wen, Yanguang, Cao, Peiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982166/
https://www.ncbi.nlm.nih.gov/pubmed/36873809
http://dx.doi.org/10.3389/fsurg.2022.966792
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author He, Yu
Qian, Liyuan
Chen, Lang
Liu, Yang
Wen, Yanguang
Cao, Peiguo
author_facet He, Yu
Qian, Liyuan
Chen, Lang
Liu, Yang
Wen, Yanguang
Cao, Peiguo
author_sort He, Yu
collection PubMed
description BACKGROUND: Primary breast angiosarcoma (PBA) is a rare sarcoma, accounting for only 0.04% of all breast malignancies, with a difficult diagnosis and a poor prognosis. Mastectomy is the standard treatment, and the role of adjuvant treatment (chemotherapy and/or radiotherapy following surgery) remains uncertain with very few studies. CASE PRESENTATION: We report the case of a 17-year-old female patient who presented with a right breast lump that had rapidly increased in size and was hemorrhaging. She was diagnosed with breast angiosarcoma by needle biopsy and pathological evaluation. However, the mass showed a quick tendency to bleed during biopsies. After that, we performed angiography and tumor vascular embolization. The patient underwent a mastectomy followed by adjuvant chemotherapy. CONCLUSION: Tumor vascular embolization reduced the surgical risk of PBA with hemorrhage complications. Postoperative therapeutic roles still need further exploration and verification.
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spelling pubmed-99821662023-03-04 Primary breast angiosarcoma: A case report He, Yu Qian, Liyuan Chen, Lang Liu, Yang Wen, Yanguang Cao, Peiguo Front Surg Surgery BACKGROUND: Primary breast angiosarcoma (PBA) is a rare sarcoma, accounting for only 0.04% of all breast malignancies, with a difficult diagnosis and a poor prognosis. Mastectomy is the standard treatment, and the role of adjuvant treatment (chemotherapy and/or radiotherapy following surgery) remains uncertain with very few studies. CASE PRESENTATION: We report the case of a 17-year-old female patient who presented with a right breast lump that had rapidly increased in size and was hemorrhaging. She was diagnosed with breast angiosarcoma by needle biopsy and pathological evaluation. However, the mass showed a quick tendency to bleed during biopsies. After that, we performed angiography and tumor vascular embolization. The patient underwent a mastectomy followed by adjuvant chemotherapy. CONCLUSION: Tumor vascular embolization reduced the surgical risk of PBA with hemorrhage complications. Postoperative therapeutic roles still need further exploration and verification. Frontiers Media S.A. 2023-02-17 /pmc/articles/PMC9982166/ /pubmed/36873809 http://dx.doi.org/10.3389/fsurg.2022.966792 Text en © 2023 He, Qian, Chen, Liu, Wen and Cao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
He, Yu
Qian, Liyuan
Chen, Lang
Liu, Yang
Wen, Yanguang
Cao, Peiguo
Primary breast angiosarcoma: A case report
title Primary breast angiosarcoma: A case report
title_full Primary breast angiosarcoma: A case report
title_fullStr Primary breast angiosarcoma: A case report
title_full_unstemmed Primary breast angiosarcoma: A case report
title_short Primary breast angiosarcoma: A case report
title_sort primary breast angiosarcoma: a case report
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982166/
https://www.ncbi.nlm.nih.gov/pubmed/36873809
http://dx.doi.org/10.3389/fsurg.2022.966792
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