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Myeloid TLR4 signaling promotes post-injury withdrawal resolution of murine liver fibrosis

The fate of resolution of liver fibrosis after withdrawal of liver injury is still incompletely elucidated. Toll-like receptor 4 (TLR4) in tissue fibroblasts is pro-fibrogenic. After withdrawal of liver injury, we unexpectedly observed a significant delay of fibrosis resolution as TLR4 signaling was...

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Detalles Bibliográficos
Autores principales:	Takimoto, Yoichi, Chu, Po-sung, Nakamoto, Nobuhiro, Hagihara, Yuya, Mikami, Yohei, Miyamoto, Kentaro, Morikawa, Rei, Teratani, Toshiaki, Taniki, Nobuhito, Fujimori, Sota, Suzuki, Takahiro, Koda, Yuzo, Ishihara, Rino, Ichikawa, Masataka, Honda, Akira, Kanai, Takanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982274/ https://www.ncbi.nlm.nih.gov/pubmed/36876136 http://dx.doi.org/10.1016/j.isci.2023.106220

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