SIC50: Determining drug inhibitory concentrations using a vision transformer and an optimized Sobel operator

As a measure of cytotoxic potency, half-maximal inhibitory concentration (IC50) is the concentration at which a drug exerts half of its maximal inhibitory effect against target cells. It can be determined by various methods that require applying additional reagents or lysing the cells. Here, we desc...

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Detalles Bibliográficos
Autores principales: Wang, Yongheng, Zhang, Weidi, Yip, Hoyin, Qu, Chuyuan, Hu, Hongru, Chen, Xiaotie, Lee, Teresa, Yang, Xi, Yang, Bingjun, Kumar, Priyadarsini, Lee, Su Yeon, Casimiro, Javier J., Zhang, Jiawei, Wang, Aijun, Lam, Kit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982297/
https://www.ncbi.nlm.nih.gov/pubmed/36873901
http://dx.doi.org/10.1016/j.patter.2023.100686

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