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COP I and II dependent trafficking controls ER-associated degradation in mammalian cells

Misfolded proteins and components of the endoplasmic reticulum (ER) quality control and ER associated degradation (ERAD) machineries concentrate in mammalian cells in the pericentriolar ER-derived quality control compartment (ERQC), suggesting it as a staging ground for ERAD. By tracking the chapero...

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Detalles Bibliográficos
Autores principales: Ogen-Shtern, Navit, Chang, Chieh, Saad, Haddas, Mazkereth, Niv, Patel, Chaitanya, Shenkman, Marina, Lederkremer, Gerardo Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982306/
https://www.ncbi.nlm.nih.gov/pubmed/36876137
http://dx.doi.org/10.1016/j.isci.2023.106232

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