Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report()

Fusarium species manifests as an opportunistic infection with intrinsic resistance to most antifungals. We present a case of a 63-year-old male with myelodysplasia who received allogeneic stem cell transplantation and presented with endophthalmitis as the initial manifestation of invasive fusariosis...

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Autores principales: Kao, Andrew S., Cramer-Bour, Cassondra, Kupsky, William, Soubani, Ayman O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982450/
https://www.ncbi.nlm.nih.gov/pubmed/36873422
http://dx.doi.org/10.1016/j.mmcr.2023.02.004
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author Kao, Andrew S.
Cramer-Bour, Cassondra
Kupsky, William
Soubani, Ayman O.
author_facet Kao, Andrew S.
Cramer-Bour, Cassondra
Kupsky, William
Soubani, Ayman O.
author_sort Kao, Andrew S.
collection PubMed
description Fusarium species manifests as an opportunistic infection with intrinsic resistance to most antifungals. We present a case of a 63-year-old male with myelodysplasia who received allogeneic stem cell transplantation and presented with endophthalmitis as the initial manifestation of invasive fusariosis that progressed to a fatal outcome despite combined intravitreal and systemic antifungal therapies. We urge clinicians to consider this complication of fusarium infection especially with the widespread use of antifungal prophylaxis that may incur selection of more resistant, invasive fungal species.
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spelling pubmed-99824502023-03-04 Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report() Kao, Andrew S. Cramer-Bour, Cassondra Kupsky, William Soubani, Ayman O. Med Mycol Case Rep Case Report Fusarium species manifests as an opportunistic infection with intrinsic resistance to most antifungals. We present a case of a 63-year-old male with myelodysplasia who received allogeneic stem cell transplantation and presented with endophthalmitis as the initial manifestation of invasive fusariosis that progressed to a fatal outcome despite combined intravitreal and systemic antifungal therapies. We urge clinicians to consider this complication of fusarium infection especially with the widespread use of antifungal prophylaxis that may incur selection of more resistant, invasive fungal species. Elsevier 2023-02-19 /pmc/articles/PMC9982450/ /pubmed/36873422 http://dx.doi.org/10.1016/j.mmcr.2023.02.004 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kao, Andrew S.
Cramer-Bour, Cassondra
Kupsky, William
Soubani, Ayman O.
Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report()
title Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report()
title_full Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report()
title_fullStr Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report()
title_full_unstemmed Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report()
title_short Endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: A case report()
title_sort endophthalmitis as the initial manifestation of invasive fusariosis in an allogeneic stem cell transplant patient: a case report()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982450/
https://www.ncbi.nlm.nih.gov/pubmed/36873422
http://dx.doi.org/10.1016/j.mmcr.2023.02.004
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