Reprogramming the tumor microenvironment leverages CD8(+) T cell responses to a shared tumor/self antigen in ovarian cancer

Tumor antigen-driven responses to weakly immunogenic self-antigens and neoantigens directly affect treatment efficacy following immunotherapy. Using orthotopically grown SV40 T antigen(+) ovarian carcinoma in antigen-naive wild-type or TgMISIIR-TAg-Low transgenic mice expressing SV40 T antigen as a...

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Detalles Bibliográficos
Autores principales: Mistarz, Anna, Winkler, Marta, Battaglia, Sebastiano, Liu, Song, Hutson, Alan, Rokita, Hanna, Gambotto, Andrea, Odunsi, Kunle O., Singh, Prashant K., McGray, A.J. Robert, Wang, Jianmin, Kozbor, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982455/
https://www.ncbi.nlm.nih.gov/pubmed/36875325
http://dx.doi.org/10.1016/j.omto.2023.02.002

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