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Developmental thyroid hormone action on pro-opiomelanocortin-expressing cells programs hypothalamic BMPR1A depletion and brown fat activation

Thyroid hormone excess secondary to global type 3 deiodinase (DIO3) deficiency leads to increased locomotor activity and reduced adiposity, but also to concurrent alterations in parameters of the leptin–melanocortin system that would predict obesity. To distinguish the underlying contributions to th...

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Detalles Bibliográficos
Autores principales:	Wu, Zhaofei, Martinez, M Elena, DeMambro, Victoria, Francois, Marie, Hernandez, Arturo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982511/ https://www.ncbi.nlm.nih.gov/pubmed/36581316 http://dx.doi.org/10.1093/jmcb/mjac078

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