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Inflammation‐Controlled Anti‐Inflammatory Hydrogels (Adv. Sci. 7/2023)

Inflammation‐Controlled Anti‐Inflammatory Hydrogels In article number 2206412, Carsten Werner, Manfred F. Maitz, and co‐workers designed an enzymatically cleavable polymer hydrogel platform for the release of anti‐inflammatory molecules in response to the inflammation status of human blood. Inflamma...

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Detalles Bibliográficos
Autores principales: Helmecke, Tina, Hahn, Dominik, Matzke, Nadine, Ferdinand, Lisa, Franke, Lars, Kühn, Sebastian, Fischer, Gunter, Werner, Carsten, Maitz, Manfred F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982520/
http://dx.doi.org/10.1002/advs.202370037
Descripción
Sumario:Inflammation‐Controlled Anti‐Inflammatory Hydrogels In article number 2206412, Carsten Werner, Manfred F. Maitz, and co‐workers designed an enzymatically cleavable polymer hydrogel platform for the release of anti‐inflammatory molecules in response to the inflammation status of human blood. Inflammation suppression reduces the release of the trigger enzyme elastase from activated granulocytes and down‐regulates hydrogel cleavage. [Image: see text]