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Artificial Diploid Escherichia coli by a CRISPR Chromosome‐Doubling Technique

Synthetic biology has been represented by the creation of artificial life forms at the genomic scale. In this work, a CRISPR‐based chromosome‐doubling technique is designed to first construct an artificial diploid Escherichia coli cell. The stable single‐cell diploid E. coli is isolated by both maxi...

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Detalles Bibliográficos
Autores principales: Wang, Pengju, Zhao, Dongdong, Li, Ju, Su, Junchang, Zhang, Chunzhi, Li, Siwei, Fan, Feiyu, Dai, Zhubo, Liao, Xiaoping, Mao, Zhitao, Bi, Changhao, Zhang, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982549/
https://www.ncbi.nlm.nih.gov/pubmed/36642845
http://dx.doi.org/10.1002/advs.202205855