Targeting GSTP1 as Therapeutic Strategy against Lung Adenocarcinoma Stemness and Resistance to Tyrosine Kinase Inhibitors

Glutathione S‐transferase pi (GSTP1), a phase II detoxification enzyme, is known to be overexpressed and mediates chemotherapeutic resistance in lung cancer. However, whether GSTP1 supports cancer stem cells (CSCs) and the underlying mechanisms in lung adenocarcinoma (LUAD) remain largely unknown. T...

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Detalles Bibliográficos
Autores principales: Wang, Si‐Qi, Chen, Jun‐Jiang, Jiang, Yuchen, Lei, Zi‐Ning, Ruan, Ye Chun, Pan, Yihang, Yam, Judy Wai Ping, Wong, Maria Pik, Xiao, Zhi‐Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982593/
https://www.ncbi.nlm.nih.gov/pubmed/36709476
http://dx.doi.org/10.1002/advs.202205262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982593/
https://www.ncbi.nlm.nih.gov/pubmed/36709476
http://dx.doi.org/10.1002/advs.202205262

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