Pain response to cannabidiol in opioid-induced hyperalgesia, acute nociceptive pain, and allodynia using a model mimicking acute pain in healthy adults in a randomized trial (CANAB II)

Opioids in general and remifentanil in particular can induce hyperalgesia. Preclinical data suggest that cannabidiol might have the capacity to reduce opioid-induced hyperalgesia (OIH). Thus, we investigated the effect of oral cannabidiol on OIH in healthy volunteers using an established pain model....

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Detalles Bibliográficos
Autores principales: Dieterle, Markus, Zurbriggen, Laura, Mauermann, Eckhard, Mercer-Chalmers-Bender, Katja, Frei, Priska, Ruppen, Wilhelm, Schneider, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982727/
https://www.ncbi.nlm.nih.gov/pubmed/35239547
http://dx.doi.org/10.1097/j.pain.0000000000002591

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