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First pan-specific vNAR against human TGF-β as a potential therapeutic application: in silico modeling assessment

Immunotherapies based on antibody fragments have been developed and applied to human diseases, describing novel antibody formats. The vNAR domains have a potential therapeutic use related to their unique properties. This work used a non-immunized Heterodontus francisci shark library to obtain a vNAR...

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Detalles Bibliográficos
Autores principales: Burciaga-Flores, Mirna, Márquez-Aguirre, Ana Laura, Dueñas, Salvador, Gasperin-Bulbarela, Jahaziel, Licea-Navarro, Alexei F., Camacho-Villegas, Tanya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982792/
https://www.ncbi.nlm.nih.gov/pubmed/36869086
http://dx.doi.org/10.1038/s41598-023-30623-x