Understanding disruption of the gut barrier during inflammation: Should we abandon traditional epithelial cell lines and switch to intestinal organoids?

Disruption of the intestinal epithelial barrier is a hallmark of mucosal inflammation. It increases exposure of the immune system to luminal microbes, triggering a perpetuating inflammatory response. For several decades, the inflammatory stimuli-induced breakdown of the human gut barrier was studied...

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Detalles Bibliográficos
Autores principales: Lechuga, Susana, Braga-Neto, Manuel B., Naydenov, Nayden G., Rieder, Florian, Ivanov, Andrei I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983034/
https://www.ncbi.nlm.nih.gov/pubmed/36875103
http://dx.doi.org/10.3389/fimmu.2023.1108289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983034/
https://www.ncbi.nlm.nih.gov/pubmed/36875103
http://dx.doi.org/10.3389/fimmu.2023.1108289

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