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Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023

From October 2022 through January 2023, nine patients with NDM-5/OXA-48-carbapenemase-producing Enterobacter hormaechei ST79 were detected in Denmark and subsequently one patient in Iceland. There were no nosocomial links between patients, but they had all been treated with dicloxacillin capsules. A...

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Autores principales: Agergaard, Charlotte Nielsen, Porsbo, Lone Jannok, Sydenham, Thomas Vognbjerg, Hansen, Sanne Grønvall Kjær, Steinke, Kat, Larsen, Sanne Løkkegaard, Helgason, Kristján Orri, Hansen, Frank, Karstensen, Kasper Thystrup, Henius, Anna E, Holzknecht, Barbara Juliane, Søes, Lillian, Schønning, Kristian, Wang, Mikala, Ank, Nina, Halldórsdóttir, Anna Margrét, Guðlaugsson, Ólafur, Hammerum, Anette M, Kjerulf, Anne, Kristensen, Brian, Hasman, Henrik, Justesen, Ulrik Stenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983070/
https://www.ncbi.nlm.nih.gov/pubmed/36862098
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.9.2300108
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author Agergaard, Charlotte Nielsen
Porsbo, Lone Jannok
Sydenham, Thomas Vognbjerg
Hansen, Sanne Grønvall Kjær
Steinke, Kat
Larsen, Sanne Løkkegaard
Helgason, Kristján Orri
Hansen, Frank
Karstensen, Kasper Thystrup
Henius, Anna E
Holzknecht, Barbara Juliane
Søes, Lillian
Schønning, Kristian
Wang, Mikala
Ank, Nina
Halldórsdóttir, Anna Margrét
Guðlaugsson, Ólafur
Hammerum, Anette M
Kjerulf, Anne
Kristensen, Brian
Hasman, Henrik
Justesen, Ulrik Stenz
author_facet Agergaard, Charlotte Nielsen
Porsbo, Lone Jannok
Sydenham, Thomas Vognbjerg
Hansen, Sanne Grønvall Kjær
Steinke, Kat
Larsen, Sanne Løkkegaard
Helgason, Kristján Orri
Hansen, Frank
Karstensen, Kasper Thystrup
Henius, Anna E
Holzknecht, Barbara Juliane
Søes, Lillian
Schønning, Kristian
Wang, Mikala
Ank, Nina
Halldórsdóttir, Anna Margrét
Guðlaugsson, Ólafur
Hammerum, Anette M
Kjerulf, Anne
Kristensen, Brian
Hasman, Henrik
Justesen, Ulrik Stenz
author_sort Agergaard, Charlotte Nielsen
collection PubMed
description From October 2022 through January 2023, nine patients with NDM-5/OXA-48-carbapenemase-producing Enterobacter hormaechei ST79 were detected in Denmark and subsequently one patient in Iceland. There were no nosocomial links between patients, but they had all been treated with dicloxacillin capsules. An NDM-5/OXA-48-carbapenemase-producing E. hormaechei ST79, identical to patient isolates, was cultured from the surface of dicloxacillin capsules in Denmark, strongly implicating them as the source of the outbreak. Special attention is required to detect the outbreak strain in the microbiology laboratory.
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spelling pubmed-99830702023-03-04 Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023 Agergaard, Charlotte Nielsen Porsbo, Lone Jannok Sydenham, Thomas Vognbjerg Hansen, Sanne Grønvall Kjær Steinke, Kat Larsen, Sanne Løkkegaard Helgason, Kristján Orri Hansen, Frank Karstensen, Kasper Thystrup Henius, Anna E Holzknecht, Barbara Juliane Søes, Lillian Schønning, Kristian Wang, Mikala Ank, Nina Halldórsdóttir, Anna Margrét Guðlaugsson, Ólafur Hammerum, Anette M Kjerulf, Anne Kristensen, Brian Hasman, Henrik Justesen, Ulrik Stenz Euro Surveill Rapid Communication From October 2022 through January 2023, nine patients with NDM-5/OXA-48-carbapenemase-producing Enterobacter hormaechei ST79 were detected in Denmark and subsequently one patient in Iceland. There were no nosocomial links between patients, but they had all been treated with dicloxacillin capsules. An NDM-5/OXA-48-carbapenemase-producing E. hormaechei ST79, identical to patient isolates, was cultured from the surface of dicloxacillin capsules in Denmark, strongly implicating them as the source of the outbreak. Special attention is required to detect the outbreak strain in the microbiology laboratory. European Centre for Disease Prevention and Control (ECDC) 2023-03-02 /pmc/articles/PMC9983070/ /pubmed/36862098 http://dx.doi.org/10.2807/1560-7917.ES.2023.28.9.2300108 Text en This article is copyright of the authors or their affiliated institutions, 2023. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Agergaard, Charlotte Nielsen
Porsbo, Lone Jannok
Sydenham, Thomas Vognbjerg
Hansen, Sanne Grønvall Kjær
Steinke, Kat
Larsen, Sanne Løkkegaard
Helgason, Kristján Orri
Hansen, Frank
Karstensen, Kasper Thystrup
Henius, Anna E
Holzknecht, Barbara Juliane
Søes, Lillian
Schønning, Kristian
Wang, Mikala
Ank, Nina
Halldórsdóttir, Anna Margrét
Guðlaugsson, Ólafur
Hammerum, Anette M
Kjerulf, Anne
Kristensen, Brian
Hasman, Henrik
Justesen, Ulrik Stenz
Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023
title Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023
title_full Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023
title_fullStr Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023
title_full_unstemmed Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023
title_short Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023
title_sort contaminated dicloxacillin capsules as the source of an ndm-5/oxa-48-producing enterobacter hormaechei st79 outbreak, denmark and iceland, 2022 and 2023
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983070/
https://www.ncbi.nlm.nih.gov/pubmed/36862098
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.9.2300108
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