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Development, initial validation, and application of a visual read method for [(18)F]MK‐6240 tau PET

BACKGROUND: The positron emission tomography (PET) radiotracer [(18)F]MK‐6240 exhibits high specificity for neurofibrillary tangles (NFTs) of tau protein in Alzheimer's disease (AD), high sensitivity to medial temporal and neocortical NFTs, and low within‐brain background. Objectives were to de...

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Detalles Bibliográficos
Autores principales: Shuping, Joanna L., Matthews, Dawn C., Adamczuk, Katarzyna, Scott, David, Rowe, Christopher C., Kreisl, William C., Johnson, Sterling C., Lukic, Ana S., Johnson, Keith A., Rosa‐Neto, Pedro, Andrews, Randolph D., Van Laere, Koen, Cordes, Lindsay, Ward, Larry, Wilde, Claire L., Barakos, Jerome, Purcell, Derk D., Devanand, Davangere P., Stern, Yaakov, Luchsinger, Jose A., Sur, Cyrille, Price, Julie C., Brickman, Adam M., Klunk, William E., Boxer, Adam L., Mathotaarachchi, Sulantha S., Lao, Patrick J., Evelhoch, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983143/
https://www.ncbi.nlm.nih.gov/pubmed/36873926
http://dx.doi.org/10.1002/trc2.12372

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