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Development, initial validation, and application of a visual read method for [(18)F]MK‐6240 tau PET
BACKGROUND: The positron emission tomography (PET) radiotracer [(18)F]MK‐6240 exhibits high specificity for neurofibrillary tangles (NFTs) of tau protein in Alzheimer's disease (AD), high sensitivity to medial temporal and neocortical NFTs, and low within‐brain background. Objectives were to de...
Autores principales: | Shuping, Joanna L., Matthews, Dawn C., Adamczuk, Katarzyna, Scott, David, Rowe, Christopher C., Kreisl, William C., Johnson, Sterling C., Lukic, Ana S., Johnson, Keith A., Rosa‐Neto, Pedro, Andrews, Randolph D., Van Laere, Koen, Cordes, Lindsay, Ward, Larry, Wilde, Claire L., Barakos, Jerome, Purcell, Derk D., Devanand, Davangere P., Stern, Yaakov, Luchsinger, Jose A., Sur, Cyrille, Price, Julie C., Brickman, Adam M., Klunk, William E., Boxer, Adam L., Mathotaarachchi, Sulantha S., Lao, Patrick J., Evelhoch, Jeffrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983143/ https://www.ncbi.nlm.nih.gov/pubmed/36873926 http://dx.doi.org/10.1002/trc2.12372 |
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