Low-dose celecoxib-loaded PCL fibers reverse intervertebral disc degeneration by up-regulating CHSY3 expression

Intervertebral disc degeneration (IDD) has been identified as one of the predominant factors leading to persistent low back pain and disability in middle-aged and elderly people. Dysregulation of Prostaglandin E2 (PGE2) can cause IDD, while low-dose celecoxib can maintain PGE2 at the physiological l...

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Detalles Bibliográficos
Autores principales: Wang, Yunhao, Zheng, Genjiang, Xie, Xiaoxing, Yu, Wei, Wang, Jianxi, Zang, Fazhi, Yang, Chen, Xiao, Qiangqiang, Zhang, Rongcheng, Wei, Leixin, Wu, Xiaodong, Liang, Lei, Cao, Peng, Xu, Chen, Li, Jing, Hu, Bo, Zhang, Tao, Wu, Jinglei, Chen, Huajiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983215/
https://www.ncbi.nlm.nih.gov/pubmed/36864461
http://dx.doi.org/10.1186/s12951-023-01823-4

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