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IL-1β contributes to the secretion of sclerostin by osteocytes and targeting sclerostin promotes spinal fusion at early stages

BACKGROUND: Despite extensive research, there is still a need for safe and effective agents to promote spinal fusion. Interleukin (IL)-1β is an important factor which influences the bone repair and remodelling. The purpose of our study was to determine the effect of IL-1β on sclerostin in osteocytes...

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Detalles Bibliográficos
Autores principales: Jiang, Zengxin, Jin, Lixia, Jiang, Chang, Yan, Zuoqin, Cao, Yuanwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983224/
https://www.ncbi.nlm.nih.gov/pubmed/36864451
http://dx.doi.org/10.1186/s13018-023-03657-0