Integrated transcriptional analysis reveals macrophage heterogeneity and macrophage-tumor cell interactions in the progression of pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease harboring significant microenvironment heterogeneity, especially for the macrophages. Tumor-associated macrophages (TAMs) orchestrate PDAC malignancy, but their dynamics during disease progression remains poorly understoo...

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Detalles Bibliográficos
Autores principales: Yang, Kaidi, Yang, Tongxin, Yu, Jian, Li, Fang, Zhao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983236/
https://www.ncbi.nlm.nih.gov/pubmed/36864399
http://dx.doi.org/10.1186/s12885-023-10675-y

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