The homeostatic function of Regnase‐2 restricts neuroinflammation

The precise physiological functions and mechanisms regulating RNase Regnase‐2 (Reg‐2/ZC3H12B/MCPIP2) activity remain enigmatic. We found that Reg‐2 actively modulates neuroinflammation in nontransformed cells, including primary astrocytes. Downregulation of Reg‐2 in these cells results in increased...

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Detalles Bibliográficos
Autores principales: Sowinska, Weronika, Wawro, Mateusz, Biswas, Debolina D., Kochan, Jakub, Pustelny, Katarzyna, Solecka, Aleksandra, Gupta, Angela S., Mockenhaupt, Karli, Polak, Jarosław, Kwinta, Borys, Kordula, Tomasz, Kasza, Aneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983307/
https://www.ncbi.nlm.nih.gov/pubmed/36753401
http://dx.doi.org/10.1096/fj.202201978R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983307/
https://www.ncbi.nlm.nih.gov/pubmed/36753401
http://dx.doi.org/10.1096/fj.202201978R

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