Cargando…

ASPP2 suppresses tumour growth and stemness characteristics in HCC by inhibiting Warburg effect via WNT/β‐catenin/HK2 axis

Abnormal energy metabolism is one of the characteristics of tumours. In the last few years, more and more attention is being paid to the role and regulation of tumour aerobic glycolysis. Cancer cells display enhanced aerobic glycolysis, also known as the Warburg effect, whereby tumour cells absorb g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Beibei, Jiang, Yuan, Song, Shaohua, Jing, Wei, Yang, Hao, Zhao, Li, Chen, Ya, Tang, Qiqi, Li, Xuhui, Zhang, Lisha, Bao, Haili, Huang, Gang, Zhao, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983321/ https://www.ncbi.nlm.nih.gov/pubmed/36752127 http://dx.doi.org/10.1111/jcmm.17687

Ejemplares similares

ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma
por: Liang, Beibei, et al.
Publicado: (2019)

Circular RNA circCUL3 Accelerates the Warburg Effect Progression of Gastric Cancer through Regulating the STAT3/HK2 Axis
por: Pu, Zhichen, et al.
Publicado: (2020)

FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer
por: Dai, Weixing, et al.
Publicado: (2020)

HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin
por: Sun, Zengpeng, et al.
Publicado: (2021)

HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin
por: Sun, Zengpeng, et al.
Publicado: (2021)

Upregulated Long Noncoding RNA UCA1 Enhances Warburg Effect via miR-203/HK2 Axis in Esophagal Cancer
por: Liu, Hai-E, et al.
Publicado: (2020)

UBR7 inhibits HCC tumorigenesis by targeting Keap1/Nrf2/Bach1/HK2 and glycolysis
por: Zhao, Liang, et al.
Publicado: (2022)

Targeted Inhibition of HK-II Reversed the Warburg Effect to Improve the Radiosensitivity of Laryngeal Carcinoma
por: Chen, Xiao-Hong, et al.
Publicado: (2021)

Roles of lncRNAs Mediating Wnt/β-Catenin Signaling in HCC
por: Xu, Yating, et al.
Publicado: (2022)

The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate
por: Lis, Paweł, et al.
Publicado: (2016)

ORY-1001 Suppresses Cell Growth and Induces Apoptosis in Lung Cancer Through Triggering HK2 Mediated Warburg Effect
por: Lu, Zhaoliang, et al.
Publicado: (2018)

Berberine inhibits the Warburg effect through TET3/miR-145/HK2 pathways in ovarian cancer cells
por: Li, Jie, et al.
Publicado: (2021)

Downregulation of DNMT3A Attenuates the Warburg Effect, Proliferation, and Invasion via Promoting the Inhibition of miR-603 on HK2 in Ovarian Cancer
por: Lu, Jiaojiao, et al.
Publicado: (2022)

BRF2 is mediated by microRNA-409-3p and promotes invasion and metastasis of HCC through the Wnt/β-catenin pathway
por: Chang, Jian-Hua, et al.
Publicado: (2023)

N(6)-methyladenosine METTL3 promotes cervical cancer tumorigenesis and Warburg effect through YTHDF1/HK2 modification
por: Wang, Qianqing, et al.
Publicado: (2020)

Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax
por: Patel, Seema, et al.
Publicado: (2008)

Sevoflurane Inhibited Osteosarcoma Cell Proliferation And Invasion Via Targeting miR-203/WNT2B/Wnt/β-Catenin Axis
por: Chen, Meixian, et al.
Publicado: (2019)

ZEB1 enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM
por: Zhou, Yanming, et al.
Publicado: (2021)

Blocking iASPP/Nrf2/M-CSF axis improves anti-cancer effect of chemotherapy-induced senescence by attenuating M2 polarization
por: Liu, Hao, et al.
Publicado: (2022)

FKN Facilitates HK-2 Cell EMT and Tubulointerstitial Lesions via the Wnt/β-Catenin Pathway in a Murine Model of Lupus Nephritis
por: Fu, Dongdong, et al.
Publicado: (2019)

Nucleostemin and ASPP2 expression is correlated with pituitary adenoma proliferation
por: MA, LIN, et al.
Publicado: (2013)

ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells
por: Wang, Y, et al.
Publicado: (2013)

miR-517a promotes Warburg effect in HCC by directly targeting FBP1
por: Zhang, Delin, et al.
Publicado: (2018)

ASPP1/2 positive patients with invasive breast cancers have good prognosis
por: Wang, Changsong, et al.
Publicado: (2023)

Downregulation of ASPP2 improves hepatocellular carcinoma cells survival via promoting BECN1-dependent autophagy initiation
por: Chen, Rui, et al.
Publicado: (2016)

CAV1 Promotes HCC Cell Progression and Metastasis through Wnt/β-Catenin Pathway
por: Yu, Hongxiu, et al.
Publicado: (2014)

ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold
por: Posada, Itziar M. D., et al.
Publicado: (2016)

ASPP2 promotes cell apoptosis in cervical cancer through inhibiting autophagy
por: Jiang, Feiyun, et al.
Publicado: (2022)

Wnt3a Promotes the Vasculogenic Mimicry Formation of Colon Cancer via Wnt/β-Catenin Signaling
por: Qi, Lisha, et al.
Publicado: (2015)

FHL2 interacts with iASPP and impacts the biological functions of leukemia cells
por: Lu, Wenting, et al.
Publicado: (2017)

ASPP: a new family of oncogenes and tumour suppressor genes
por: Sullivan, A, et al.
Publicado: (2007)

UBQLN4 promotes progression of HCC via activating wnt-β-catenin pathway and is regulated by miR-370
por: Yu, Yan, et al.
Publicado: (2020)

Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73
por: Canning, Peter, et al.
Publicado: (2012)

Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy
por: Chen, Xiao-Li, et al.
Publicado: (2016)

Circular RNA circRNF20 promotes breast cancer tumorigenesis and Warburg effect through miR-487a/HIF-1α/HK2
por: Cao, Lili, et al.
Publicado: (2020)

HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth
por: Pandolfi, S, et al.
Publicado: (2015)

Novel mitochondrion‐targeting copper(II) complex induces HK2 malfunction and inhibits glycolysis via Drp1‐mediating mitophagy in HCC
por: Li, Mengmeng, et al.
Publicado: (2020)

Chronic alcohol exposure promotes HCC stemness and metastasis through β-catenin/miR-22-3p/TET2 axis
por: Chen, Danlei, et al.
Publicado: (2021)

ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis
por: Royer, Christophe, et al.
Publicado: (2022)

ZNF671 Inhibits the Proliferation and Metastasis of NSCLC via the Wnt/β-Catenin Pathway
por: Zhan, Wei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0mlueiilumbvv12mgnka82de2e