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ULK1 Depletion Protects Mice from Diethylnitrosamine-Induced Hepatocarcinogenesis by Promoting Apoptosis and Inhibiting Autophagy
PURPOSE: The uncoordinated-51 like kinase 1 (ULK1) is an important serine/threonine protein kinase involved in autophagy, especially for the initiation stage. Previous studies have shown that ULK1 could be used as a prognostic marker in predicting poor progression-free survival and a therapeutic tar...
Autores principales: | Duan, Ting, Yang, Xin, Kuang, Jingyu, Sun, Wenjie, Li, Jin, Ge, Juan, Zhang, Mohan, Cai, Xiaobo, Yu, Peilin, Yang, Jun, Zhu, Xinqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983443/ https://www.ncbi.nlm.nih.gov/pubmed/36874251 http://dx.doi.org/10.2147/JHC.S399855 |
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