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Modeling interaction of Glioma cells and CAR T-cells considering multiple CAR T-cells bindings

Chimeric antigen receptor (CAR) T-cell based immunotherapy has shown its potential in treating blood cancers, and its application to solid tumors is currently being extensively investigated. For glioma brain tumors, various CAR T-cell targets include IL13Rα2, EGFRvIII, HER2, EphA2, GD2, B7-H3, and c...

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Detalles Bibliográficos
Autores principales: Li, Runpeng, Sahoo, Prativa, Wang, Dongrui, Wang, Qixuan, Brown, Christine E., Rockne, Russell C., Cho, Heyrim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983577/
https://www.ncbi.nlm.nih.gov/pubmed/36875891
http://dx.doi.org/10.1016/j.immuno.2023.100022