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Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite
BACKGROUND: Snakebite is a significant occupational and environmental hazard in tropical countries. The treatment of snakebite includes care of the wound, supportive care, and administration of anti-snake venom (ASV). Time is crucial to reducing the morbidity and mortality of patients. This study ai...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Jaypee Brothers Medical Publishers
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983646/ https://www.ncbi.nlm.nih.gov/pubmed/36873588 http://dx.doi.org/10.5005/jp-journals-10071-24344 |
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author | Jayaraman, Thamizhkumaran Dhanasinghu, Raju Kuppusamy, Santhanam Gaur, Archana Sakthivadivel, Varatharajan |
author_facet | Jayaraman, Thamizhkumaran Dhanasinghu, Raju Kuppusamy, Santhanam Gaur, Archana Sakthivadivel, Varatharajan |
author_sort | Jayaraman, Thamizhkumaran |
collection | PubMed |
description | BACKGROUND: Snakebite is a significant occupational and environmental hazard in tropical countries. The treatment of snakebite includes care of the wound, supportive care, and administration of anti-snake venom (ASV). Time is crucial to reducing the morbidity and mortality of patients. This study aimed to assess the “bite-to-needle time” with morbidity and mortality of snakebites and correlate it. PATIENTS AND METHODS: A total of 100 patients were included. Detailed history included the time since snakebite, bite site, species of snake, and symptoms at presentation, which included level of consciousness, cellulitis, ptosis, respiratory failure, oliguria, and bleeding manifestations. “Bite-to-needle time” was noted. Polyvalent ASV was administered in all patients. Duration of hospitalization and complications, including mortality were noted. RESULTS: The age-group of the study population was 20–60 years. About 68% were males. Krait was the commonest species (40%), and the lower limb was the commonest bite site. Within 6 hours, 36% of patients received ASV, and between 6 and 12 hours, 30%. Patients with a bite-to-needle time of under 6 hours spent less time in the hospital and experienced fewer complications. Patients with bite-to-needle times longer than 24 hours had more ASV vials, complications, hospital-stay length, and death. CONCLUSION: An increase in bite-to-needle time increases the chances of systemic envenomation, hence, the severity of complications or morbidity and risk of mortality increases. The necessity of timing and the value of administering ASV on time must be emphasized to the patients. HOW TO CITE THIS ARTICLE: Jayaraman T, Dhanasinghu R, Kuppusamy S, Gaur A, Sakthivadivel V. Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite. Indian J Crit Care Med 2022;26(11):1175–1178. |
format | Online Article Text |
id | pubmed-9983646 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Jaypee Brothers Medical Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-99836462023-03-04 Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite Jayaraman, Thamizhkumaran Dhanasinghu, Raju Kuppusamy, Santhanam Gaur, Archana Sakthivadivel, Varatharajan Indian J Crit Care Med Original Article BACKGROUND: Snakebite is a significant occupational and environmental hazard in tropical countries. The treatment of snakebite includes care of the wound, supportive care, and administration of anti-snake venom (ASV). Time is crucial to reducing the morbidity and mortality of patients. This study aimed to assess the “bite-to-needle time” with morbidity and mortality of snakebites and correlate it. PATIENTS AND METHODS: A total of 100 patients were included. Detailed history included the time since snakebite, bite site, species of snake, and symptoms at presentation, which included level of consciousness, cellulitis, ptosis, respiratory failure, oliguria, and bleeding manifestations. “Bite-to-needle time” was noted. Polyvalent ASV was administered in all patients. Duration of hospitalization and complications, including mortality were noted. RESULTS: The age-group of the study population was 20–60 years. About 68% were males. Krait was the commonest species (40%), and the lower limb was the commonest bite site. Within 6 hours, 36% of patients received ASV, and between 6 and 12 hours, 30%. Patients with a bite-to-needle time of under 6 hours spent less time in the hospital and experienced fewer complications. Patients with bite-to-needle times longer than 24 hours had more ASV vials, complications, hospital-stay length, and death. CONCLUSION: An increase in bite-to-needle time increases the chances of systemic envenomation, hence, the severity of complications or morbidity and risk of mortality increases. The necessity of timing and the value of administering ASV on time must be emphasized to the patients. HOW TO CITE THIS ARTICLE: Jayaraman T, Dhanasinghu R, Kuppusamy S, Gaur A, Sakthivadivel V. Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite. Indian J Crit Care Med 2022;26(11):1175–1178. Jaypee Brothers Medical Publishers 2022-11 /pmc/articles/PMC9983646/ /pubmed/36873588 http://dx.doi.org/10.5005/jp-journals-10071-24344 Text en Copyright © 2022; Jaypee Brothers Medical Publishers (P) Ltd. https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2022 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Original Article Jayaraman, Thamizhkumaran Dhanasinghu, Raju Kuppusamy, Santhanam Gaur, Archana Sakthivadivel, Varatharajan Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite |
title | Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite |
title_full | Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite |
title_fullStr | Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite |
title_full_unstemmed | Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite |
title_short | Bite-to-needle Time – An Extrapolative Indicator of Repercussion in Patients with Snakebite |
title_sort | bite-to-needle time – an extrapolative indicator of repercussion in patients with snakebite |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983646/ https://www.ncbi.nlm.nih.gov/pubmed/36873588 http://dx.doi.org/10.5005/jp-journals-10071-24344 |
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