Cargando…
24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression
PURPOSE: The purpose of this study was to compare 24-hour intraocular pressure (IOP) related fluctuations monitoring between 2 groups of visual field progression rates in patients with open angle glaucoma (OAG). METHODS: Cross-sectional study performed at Bordeaux University Hospital. Twenty-four-ho...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983699/ https://www.ncbi.nlm.nih.gov/pubmed/36862120 http://dx.doi.org/10.1167/iovs.64.3.3 |
_version_ | 1784900601740525568 |
---|---|
author | Gaboriau, Thibaut Dubois, Remi Foucque, Boris Malet, Florence Schweitzer, Cedric |
author_facet | Gaboriau, Thibaut Dubois, Remi Foucque, Boris Malet, Florence Schweitzer, Cedric |
author_sort | Gaboriau, Thibaut |
collection | PubMed |
description | PURPOSE: The purpose of this study was to compare 24-hour intraocular pressure (IOP) related fluctuations monitoring between 2 groups of visual field progression rates in patients with open angle glaucoma (OAG). METHODS: Cross-sectional study performed at Bordeaux University Hospital. Twenty-four-hour monitoring was performed using a contact lens sensor (CLS; Triggerfish; SENSIMED, Etagnières, Switzerland). Progression rate was calculated using a linear regression of the mean deviation (MD) parameter of the visual field test (Octopus; HAAG-STREIT, Switzerland). Patients were allocated into two groups: group 1 with an MD progression rate <−0.5 dB/year and group 2 with an MD progression rate ≥−0.5 dB/year. An automatic signal-processing program was developed and a frequency filtering of the monitoring by wavelet transform analysis was used to compare the output signal between the two groups. A multivariate classifier was performed for prediction of the faster progression group. RESULTS: Fifty-four eyes of 54 patients were included. The mean progression rate was −1.09 ± 0.60 dB/year in group 1 (n = 22) and −0.12 ± 0.13 dB/year in group 2 (n = 32). Twenty-four-hour magnitude and absolute area under the monitoring curve were significantly higher in group 1 than in group 2 (group 1: 343.1 ± 62.3 millivolts [mVs] and 8.28 ± 2.10 mVs, respectively, group 2: 274.0 ± 75.0 mV and 6.82 ± 2.70 mVs respectively, P < 0.05). Magnitude and area under the wavelet curve for short frequency periods ranging from 60 to 220 minutes were also significantly higher in group 1 (P < 0.05). CONCLUSIONS: The 24-hour IOP related fluctuations characteristics, as assessed by a CLS, may act as a risk factor for progression in OAG. In association with other predictive factors of glaucoma progression, the CLS may help adjust treatment strategy earlier. |
format | Online Article Text |
id | pubmed-9983699 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Association for Research in Vision and Ophthalmology |
record_format | MEDLINE/PubMed |
spelling | pubmed-99836992023-03-04 24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression Gaboriau, Thibaut Dubois, Remi Foucque, Boris Malet, Florence Schweitzer, Cedric Invest Ophthalmol Vis Sci Glaucoma PURPOSE: The purpose of this study was to compare 24-hour intraocular pressure (IOP) related fluctuations monitoring between 2 groups of visual field progression rates in patients with open angle glaucoma (OAG). METHODS: Cross-sectional study performed at Bordeaux University Hospital. Twenty-four-hour monitoring was performed using a contact lens sensor (CLS; Triggerfish; SENSIMED, Etagnières, Switzerland). Progression rate was calculated using a linear regression of the mean deviation (MD) parameter of the visual field test (Octopus; HAAG-STREIT, Switzerland). Patients were allocated into two groups: group 1 with an MD progression rate <−0.5 dB/year and group 2 with an MD progression rate ≥−0.5 dB/year. An automatic signal-processing program was developed and a frequency filtering of the monitoring by wavelet transform analysis was used to compare the output signal between the two groups. A multivariate classifier was performed for prediction of the faster progression group. RESULTS: Fifty-four eyes of 54 patients were included. The mean progression rate was −1.09 ± 0.60 dB/year in group 1 (n = 22) and −0.12 ± 0.13 dB/year in group 2 (n = 32). Twenty-four-hour magnitude and absolute area under the monitoring curve were significantly higher in group 1 than in group 2 (group 1: 343.1 ± 62.3 millivolts [mVs] and 8.28 ± 2.10 mVs, respectively, group 2: 274.0 ± 75.0 mV and 6.82 ± 2.70 mVs respectively, P < 0.05). Magnitude and area under the wavelet curve for short frequency periods ranging from 60 to 220 minutes were also significantly higher in group 1 (P < 0.05). CONCLUSIONS: The 24-hour IOP related fluctuations characteristics, as assessed by a CLS, may act as a risk factor for progression in OAG. In association with other predictive factors of glaucoma progression, the CLS may help adjust treatment strategy earlier. The Association for Research in Vision and Ophthalmology 2023-03-02 /pmc/articles/PMC9983699/ /pubmed/36862120 http://dx.doi.org/10.1167/iovs.64.3.3 Text en Copyright 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
spellingShingle | Glaucoma Gaboriau, Thibaut Dubois, Remi Foucque, Boris Malet, Florence Schweitzer, Cedric 24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression |
title | 24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression |
title_full | 24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression |
title_fullStr | 24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression |
title_full_unstemmed | 24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression |
title_short | 24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression |
title_sort | 24-hour monitoring of intraocular pressure fluctuations using a contact lens sensor: diagnostic performance for glaucoma progression |
topic | Glaucoma |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983699/ https://www.ncbi.nlm.nih.gov/pubmed/36862120 http://dx.doi.org/10.1167/iovs.64.3.3 |
work_keys_str_mv | AT gaboriauthibaut 24hourmonitoringofintraocularpressurefluctuationsusingacontactlenssensordiagnosticperformanceforglaucomaprogression AT duboisremi 24hourmonitoringofintraocularpressurefluctuationsusingacontactlenssensordiagnosticperformanceforglaucomaprogression AT foucqueboris 24hourmonitoringofintraocularpressurefluctuationsusingacontactlenssensordiagnosticperformanceforglaucomaprogression AT maletflorence 24hourmonitoringofintraocularpressurefluctuationsusingacontactlenssensordiagnosticperformanceforglaucomaprogression AT schweitzercedric 24hourmonitoringofintraocularpressurefluctuationsusingacontactlenssensordiagnosticperformanceforglaucomaprogression |