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Morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes

OBJECTIVE: This study aims to evaluate the impact of morning-evening preference in pregnancy outcomes in gestational diabetes mellitus (GDM). MATERIALS AND METHODS: This is a prospective cohort study of 2nd-3rd trimester GDM outpatient care in Fortaleza, Brazil (2018-2020). Eveningness was defined b...

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Autores principales: Facanha, Cristina Figueiredo Sampaio, Alencar, Victória Sudário, Machado, Paula Soares, Macêdo, Rejane Belchior Lima, de Bruin, Pedro Felipe Carvalhedo, Forti, Adriana Costa e, Rocha, Thaine Mirla, de Bruin, Veralice Meireles Sales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983797/
https://www.ncbi.nlm.nih.gov/pubmed/36155121
http://dx.doi.org/10.20945/2359-3997000000515
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author Facanha, Cristina Figueiredo Sampaio
Alencar, Victória Sudário
Machado, Paula Soares
Macêdo, Rejane Belchior Lima
de Bruin, Pedro Felipe Carvalhedo
Forti, Adriana Costa e
Rocha, Thaine Mirla
de Bruin, Veralice Meireles Sales
author_facet Facanha, Cristina Figueiredo Sampaio
Alencar, Victória Sudário
Machado, Paula Soares
Macêdo, Rejane Belchior Lima
de Bruin, Pedro Felipe Carvalhedo
Forti, Adriana Costa e
Rocha, Thaine Mirla
de Bruin, Veralice Meireles Sales
author_sort Facanha, Cristina Figueiredo Sampaio
collection PubMed
description OBJECTIVE: This study aims to evaluate the impact of morning-evening preference in pregnancy outcomes in gestational diabetes mellitus (GDM). MATERIALS AND METHODS: This is a prospective cohort study of 2nd-3rd trimester GDM outpatient care in Fortaleza, Brazil (2018-2020). Eveningness was defined by the Horne-Östberg Morningness-Eveningness-Questionnaire (MEQ ≤ 41). Furthermore, we obtained a 7-day actigraphic register. Subjective sleep quality, daytime somnolence, insomnia, fatigue and depressive symptoms were also evaluated. Associations with pregnancy outcomes were investigated. RESULTS: Among 305 patients with GDM, evening preference was found in 21 (6.9%). Patients with evening preference had worse sleep quality (p < 0.01), greater severity of insomnia (p < 0.005), fatigue (p < 0.005) and depressive symptoms (<0.009). Evening chronotype was associated with preeclampsia [p = 0.01; OR = 0.27; CI 0.09-0.79] and a greater need for admission to a neonatal intensive care unit (NICU) [p = 0.02; OR = 0.23; CI .0.06-0.80]. A lower MEQ score confirmed an association with preeclampsia [p = 0.002; OR = 0.94; CI 0.90-0.97] and this was maintained after controlling for age, arterial hypertension, sleep quality, fatigue and depressive symptoms [p < 005; OR = 0.91; CI 0.87-0.95]. CONCLUSION: In GDM, patients with evening preference had worse sleep quality, more insomnia, fatigue, and depressive symptoms. Furthermore, eveningness was independently associated with preeclampsia. These results indicate the important role of eveningness in adverse pregnancy outcomes.
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spelling pubmed-99837972023-03-14 Morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes Facanha, Cristina Figueiredo Sampaio Alencar, Victória Sudário Machado, Paula Soares Macêdo, Rejane Belchior Lima de Bruin, Pedro Felipe Carvalhedo Forti, Adriana Costa e Rocha, Thaine Mirla de Bruin, Veralice Meireles Sales Arch Endocrinol Metab Original Article OBJECTIVE: This study aims to evaluate the impact of morning-evening preference in pregnancy outcomes in gestational diabetes mellitus (GDM). MATERIALS AND METHODS: This is a prospective cohort study of 2nd-3rd trimester GDM outpatient care in Fortaleza, Brazil (2018-2020). Eveningness was defined by the Horne-Östberg Morningness-Eveningness-Questionnaire (MEQ ≤ 41). Furthermore, we obtained a 7-day actigraphic register. Subjective sleep quality, daytime somnolence, insomnia, fatigue and depressive symptoms were also evaluated. Associations with pregnancy outcomes were investigated. RESULTS: Among 305 patients with GDM, evening preference was found in 21 (6.9%). Patients with evening preference had worse sleep quality (p < 0.01), greater severity of insomnia (p < 0.005), fatigue (p < 0.005) and depressive symptoms (<0.009). Evening chronotype was associated with preeclampsia [p = 0.01; OR = 0.27; CI 0.09-0.79] and a greater need for admission to a neonatal intensive care unit (NICU) [p = 0.02; OR = 0.23; CI .0.06-0.80]. A lower MEQ score confirmed an association with preeclampsia [p = 0.002; OR = 0.94; CI 0.90-0.97] and this was maintained after controlling for age, arterial hypertension, sleep quality, fatigue and depressive symptoms [p < 005; OR = 0.91; CI 0.87-0.95]. CONCLUSION: In GDM, patients with evening preference had worse sleep quality, more insomnia, fatigue, and depressive symptoms. Furthermore, eveningness was independently associated with preeclampsia. These results indicate the important role of eveningness in adverse pregnancy outcomes. Sociedade Brasileira de Endocrinologia e Metabologia 2022-09-20 /pmc/articles/PMC9983797/ /pubmed/36155121 http://dx.doi.org/10.20945/2359-3997000000515 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Facanha, Cristina Figueiredo Sampaio
Alencar, Victória Sudário
Machado, Paula Soares
Macêdo, Rejane Belchior Lima
de Bruin, Pedro Felipe Carvalhedo
Forti, Adriana Costa e
Rocha, Thaine Mirla
de Bruin, Veralice Meireles Sales
Morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes
title Morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes
title_full Morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes
title_fullStr Morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes
title_full_unstemmed Morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes
title_short Morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes
title_sort morningness/eveningness in gestational diabetes mellitus: clinical characteristics and maternal-neonatal outcomes
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983797/
https://www.ncbi.nlm.nih.gov/pubmed/36155121
http://dx.doi.org/10.20945/2359-3997000000515
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