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Kinome inhibition states and multiomics data enable prediction of cell viability in diverse cancer types

Protein kinases play a vital role in a wide range of cellular processes, and compounds that inhibit kinase activity emerging as a primary focus for targeted therapy development, especially in cancer. Consequently, efforts to characterize the behavior of kinases in response to inhibitor treatment, as...

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Detalles Bibliográficos
Autores principales: Berginski, Matthew E., Joisa, Chinmaya U., Golitz, Brian T., Gomez, Shawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983880/
https://www.ncbi.nlm.nih.gov/pubmed/36809237
http://dx.doi.org/10.1371/journal.pcbi.1010888

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