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Kinome inhibition states and multiomics data enable prediction of cell viability in diverse cancer types
Protein kinases play a vital role in a wide range of cellular processes, and compounds that inhibit kinase activity emerging as a primary focus for targeted therapy development, especially in cancer. Consequently, efforts to characterize the behavior of kinases in response to inhibitor treatment, as...
Autores principales: | Berginski, Matthew E., Joisa, Chinmaya U., Golitz, Brian T., Gomez, Shawn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983880/ https://www.ncbi.nlm.nih.gov/pubmed/36809237 http://dx.doi.org/10.1371/journal.pcbi.1010888 |
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