Cargando…

RNA localization mechanisms transcend cell morphology

RNA molecules are localized to specific subcellular regions through interactions between RNA regulatory elements and RNA binding proteins (RBPs). Generally, our knowledge of the mechanistic details behind the localization of a given RNA is restricted to a particular cell type. Here, we show that RNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goering, Raeann, Arora, Ankita, Pockalny, Megan C, Taliaferro, J Matthew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984196/ https://www.ncbi.nlm.nih.gov/pubmed/36867563 http://dx.doi.org/10.7554/eLife.80040

Ejemplares similares

FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences
por: Goering, Raeann, et al.
Publicado: (2020)

Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells
por: Swygert, Sarah G, et al.
Publicado: (2021)

Translation affects mRNA stability in a codon-dependent manner in human cells
por: Wu, Qiushuang, et al.
Publicado: (2019)

The Role of Alternative Polyadenylation in the Regulation of Subcellular RNA Localization
por: Arora, Ankita, et al.
Publicado: (2022)

Morphological and genomic shifts in mole-rat ‘queens’ increase fecundity but reduce skeletal integrity
por: Johnston, Rachel A, et al.
Publicado: (2021)

Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m(6)A modification
por: Parker, Matthew T, et al.
Publicado: (2020)

RNA Polymerase II transcription independent of TBP in murine embryonic stem cells
por: Kwan, James ZJ, et al.
Publicado: (2023)

Local genetic context shapes the function of a gene regulatory network
por: Nagy-Staron, Anna, et al.
Publicado: (2021)

An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning
por: Ehrmann, Ingrid, et al.
Publicado: (2019)

A local ATR-dependent checkpoint pathway is activated by a site-specific replication fork block in human cells
por: Ahmed-Seghir, Sana, et al.
Publicado: (2023)

GC content shapes mRNA storage and decay in human cells
por: Courel, Maïté, et al.
Publicado: (2019)

m(6)A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5’ splice site
por: Parker, Matthew T, et al.
Publicado: (2022)

Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription
por: Gilbertson, Sarah, et al.
Publicado: (2018)

Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts
por: Bell, Jason C, et al.
Publicado: (2018)

ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity
por: Moore, Michael J, et al.
Publicado: (2018)

Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes
por: Raz, Amelie A, et al.
Publicado: (2023)

The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis
por: Ivanyi-Nagy, Roland, et al.
Publicado: (2018)

PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment
por: Imai, Yukiko, et al.
Publicado: (2020)

CTCF confers local nucleosome resiliency after DNA replication and during mitosis
por: Owens, Nick, et al.
Publicado: (2019)

A tudor domain protein, SIMR-1, promotes siRNA production at piRNA-targeted mRNAs in C. elegans
por: Manage, Kevin I, et al.
Publicado: (2020)

Avoiding false discoveries in single-cell RNA-seq by revisiting the first Alzheimer’s disease dataset
por: Murphy, Alan E, et al.
Publicado: (2023)

Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells
por: Freimer, Jacob W, et al.
Publicado: (2018)

MicroRNA-deficient mouse embryonic stem cells acquire a functional interferon response
por: Witteveldt, Jeroen, et al.
Publicado: (2019)

Sae2/CtIP prevents R-loop accumulation in eukaryotic cells
por: Makharashvili, Nodar, et al.
Publicado: (2018)

Hydrop enables droplet-based single-cell ATAC-seq and single-cell RNA-seq using dissolvable hydrogel beads
por: De Rop, Florian V, et al.
Publicado: (2022)

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart
por: Taliani, Valeria, et al.
Publicado: (2023)

The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway
por: Hao, Qinyu, et al.
Publicado: (2020)

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit
por: Milligan, Laura, et al.
Publicado: (2017)

mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding
por: Bao, Chen, et al.
Publicado: (2020)

The RNA-binding protein SFPQ preserves long-intron splicing and regulates circRNA biogenesis in mammals
por: Stagsted, Lotte Victoria Winther, et al.
Publicado: (2021)

Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development
por: Zhou, Li, et al.
Publicado: (2018)

Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability
por: Chan, Leon Y, et al.
Publicado: (2018)

An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning
por: Díaz-López, Irene, et al.
Publicado: (2019)

The modular mechanism of chromocenter formation in Drosophila
por: Jagannathan, Madhav, et al.
Publicado: (2019)

Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability
por: Vijjamarri, Anil Kumar, et al.
Publicado: (2023)

A simple mechanism for integration of quorum sensing and cAMP signalling in Vibrio cholerae
por: Walker, Lucas M, et al.
Publicado: (2023)

Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis
por: Prasada Rao, Hanumanthu BD, et al.
Publicado: (2021)

The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology
por: Fu, Yu, et al.
Publicado: (2018)

A new protocol for single-cell RNA-seq reveals stochastic gene expression during lag phase in budding yeast
por: Jariani, Abbas, et al.
Publicado: (2020)

Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction
por: Ranjan, Anand, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cuv6mhf6b5h8bp6coqk8kivmg7