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Integrin-KCNB1 potassium channel complexes regulate neocortical neuronal development and are implicated in epilepsy

Potassium (K(+)) channels are robustly expressed during prenatal brain development, including in progenitor cells and migrating neurons, but their function is poorly understood. Here, we investigate the role of voltage-gated K(+) channel KCNB1 (Kv2.1) in neocortical development. Neuronal migration o...

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Detalles Bibliográficos
Autores principales: Bortolami, Alessandro, Yu, Wei, Forzisi, Elena, Ercan, Koray, Kadakia, Ritik, Murugan, Madhuvika, Fedele, Denise, Estevez, Irving, Boison, Detlev, Rasin, Mladen-Roko, Sesti, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984485/
https://www.ncbi.nlm.nih.gov/pubmed/36207442
http://dx.doi.org/10.1038/s41418-022-01072-2

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