Cargando…

Cryo-EM structure of human heptameric pannexin 2 channel

Pannexin 2 (Panx2) is a large-pore ATP-permeable channel with critical roles in various physiological processes, such as the inflammatory response, energy production and apoptosis. Its dysfunction is related to numerous pathological conditions including ischemic brain injury, glioma and glioblastoma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hang, Wang, Shiyu, Zhang, Zhenzhen, Hou, Mengzhuo, Du, Chunyu, Zhao, Zhenye, Vogel, Horst, Li, Zhifang, Yan, Kaige, Zhang, Xiaokang, Lu, Jianping, Liang, Yujie, Yuan, Shuguang, Wang, Daping, Zhang, Huawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984531/ https://www.ncbi.nlm.nih.gov/pubmed/36869038 http://dx.doi.org/10.1038/s41467-023-36861-x

Ejemplares similares

Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
por: Ma, Tao, et al.
Publicado: (2023)

Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel
por: Ren, Yue, et al.
Publicado: (2022)

Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly
por: Takahashi, Hirohide, et al.
Publicado: (2023)

Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2
por: Zhu, Kongfu, et al.
Publicado: (2022)

Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders
por: Zhang, Zhenzhen, et al.
Publicado: (2022)

Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state
por: Antoni, Claudia, et al.
Publicado: (2020)

The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition
por: Michalski, Kevin, et al.
Publicado: (2020)

The 2.4 Å cryo-EM structure of a heptameric light-harvesting 2 complex reveals two carotenoid energy transfer pathways
por: Gardiner, Alastair T., et al.
Publicado: (2021)

Cryo-EM Structure of a Begomovirus Geminate Particle
por: Xu, Xiongbiao, et al.
Publicado: (2019)

Applications and prospects of cryo-EM in drug discovery
por: Zhu, Kong-Fu, et al.
Publicado: (2023)

Crystal structure and biochemical analysis of the heptameric Lsm1-7 complex
por: Zhou, Lijun, et al.
Publicado: (2014)

CryoEM structure of the mature dengue virus at 3.5-Å resolution
por: Zhang, Xiaokang, et al.
Publicado: (2012)

Studying bacterial chemosensory array with CryoEM
por: Qin, Zhuan, et al.
Publicado: (2021)

Cryo-EM advances in RNA structure determination
por: Ma, Haiyun, et al.
Publicado: (2022)

Architecture of the baculovirus nucleocapsid revealed by cryo-EM
por: Jia, Xudong, et al.
Publicado: (2023)

Cryo-EM structure of an active central apparatus
por: Han, Long, et al.
Publicado: (2022)

Structure–function mapping of a heptameric module in the nuclear pore complex
por: Fernandez-Martinez, Javier, et al.
Publicado: (2012)

Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase
por: Yang, Xiaoli, et al.
Publicado: (2022)

A snapshot of cryo‐EM
por: Skiniotis, Georgios
Publicado: (2016)

Interpreting the cryo-EM map
por: Rosenthal, Peter B.
Publicado: (2019)

COVID-19 and cryo-EM
por: Subramaniam, Sriram
Publicado: (2020)

Cryo-EM at ACA 2022
por: Subramaniam, Sriram, et al.
Publicado: (2022)

Tools for the cryo-EM gold rush: going from the cryo-EM map to the atomistic model
por: Kim, Doo Nam, et al.
Publicado: (2017)

Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter
por: Zhang, Yuanyuan, et al.
Publicado: (2020)

Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution
por: Zhang, Kaiming, et al.
Publicado: (2019)

Heptameric Targeting Ligands against EGFR and HER2 with High Stability and Avidity
por: Kim, Dongwook, et al.
Publicado: (2012)

Heptameric Peptide Interferes with Amyloid-β Aggregation by Structural Reorganization of the Toxic Oligomers
por: Bhattacharyya, Rajanya, et al.
Publicado: (2020)

Cryo-EM structure of the human sodium-chloride cotransporter NCC
por: Nan, Jing, et al.
Publicado: (2022)

Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM
por: Li, Shanshan, et al.
Publicado: (2022)

Exploring applications of crowdsourcing to cryo-EM
por: Bruggemann, Jacob, et al.
Publicado: (2018)

Cryo-EM Structure of the Exocyst Complex
por: Mei, Kunrong, et al.
Publicado: (2018)

Density modification of cryo-EM maps
por: Terwilliger, Thomas C., et al.
Publicado: (2020)

Fast multiscale reconstruction for Cryo-EM()
por: Donati, Laurène, et al.
Publicado: (2018)

Cryo‐EM targets in CASP14
por: Cragnolini, Tristan, et al.
Publicado: (2021)

Cryo-EM structure of the SEA complex
por: Tafur, Lucas, et al.
Publicado: (2022)

Cryo‐EM structures of coagulation factors
por: Di Cera, Enrico, et al.
Publicado: (2022)

To Be or Not to Be an Ion Channel: Cryo-EM Structures Have a Say
por: Chen, Gui-Lan, et al.
Publicado: (2023)

Cryo-electron Tomography Reveals the Roles of FliY in Helicobacter pylori Flagellar Motor Assembly
por: Lu, Ping, et al.
Publicado: (2022)

Oroxylin A Inhibits Hemolysis via Hindering the Self-Assembly of α-Hemolysin Heptameric Transmembrane Pore
por: Dong, Jing, et al.
Publicado: (2013)

Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM
por: Liu, Nan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_da7s6fem9rcipmnenn50k9d5qc