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Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

Single ribonucleoside monophosphates (rNMPs) are transiently present in eukaryotic genomes. The RNase H2-dependent ribonucleotide excision repair (RER) pathway ensures error-free rNMP removal. In some pathological conditions, rNMP removal is impaired. If these rNMPs hydrolyze during, or prior to, S...

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Detalles Bibliográficos
Autores principales: Schindler, Natalie, Tonn, Matthias, Kellner, Vanessa, Fung, Jia Jun, Lockhart, Arianna, Vydzhak, Olga, Juretschke, Thomas, Möckel, Stefanie, Beli, Petra, Khmelinskii, Anton, Luke, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984532/
https://www.ncbi.nlm.nih.gov/pubmed/36869098
http://dx.doi.org/10.1038/s41467-023-36866-6