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Acid-sensing ion channel 1a activates IK(Ca)/SK(Ca) channels and contributes to endothelium-dependent dilation

Acid-sensing ion channel 1a (ASIC1a) belongs to a novel family of proton-gated cation channels that are permeable to both Na(+) and Ca(2+). ASIC1a is expressed in vascular smooth muscle and endothelial cells in a variety of vascular beds, yet little is known regarding the potential impact of ASIC1a...

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Detalles Bibliográficos
Autores principales: Garcia, Selina M., Naik, Jay S., Resta, Thomas C., Jernigan, Nikki L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984545/
https://www.ncbi.nlm.nih.gov/pubmed/36484717
http://dx.doi.org/10.1085/jgp.202213173