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Separation of highly hydrophilic nicotinamide metabolites using a COSMOSIL PBr column

Highly hydrophilic compounds such as nicotinamide metabolites are very difficult to separate via high-performance liquid chromatography (HPLC) using octadecyl (C(18)) columns. In general, for the separation of hydrophilic compounds, hydrophilic interaction liquid chromatography (HILIC) columns are u...

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Detalles Bibliográficos
Autores principales:	Ozaki, Makoto, Shimotsuma, Motoshi, Hirose, Tsunehisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Protocol Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984678/ https://www.ncbi.nlm.nih.gov/pubmed/36879763 http://dx.doi.org/10.1016/j.mex.2023.102061

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