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Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study
INTRODUCTION: EGFR mutations drive a subset of NSCLC. Patients harboring the common EGFR mutations, deletion of exon 19 and L858R, respond well to osimertinib, a third-generation tyrosine kinase inhibitor. Nevertheless, the effect of osimertinib on NSCLC with atypical EGFR mutations is not well desc...
Autores principales: | Ji, Jingran, Aredo, Jacqueline V., Piper-Vallillo, Andrew, Huppert, Laura, Rotow, Julia K., Husain, Hatim, Stewart, Susan, Cobb, Rosemary, Wakelee, Heather A., Blakely, Collin M., Wong, Melisa L., Gubens, Matthew A., Madani, Mohammad H., Digumarthy, Subba R., McCoach, Caroline, Piotrowska, Zofia, Neal, Joel W., Riess, Jonathan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984841/ https://www.ncbi.nlm.nih.gov/pubmed/36879929 http://dx.doi.org/10.1016/j.jtocrr.2022.100459 |
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