Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of small to medium vessels. Gastrointestinal involvement is uncommon and is associated with higher mortality. Treatment is based on empiric evidence. In this article, we report a case of EGPA-related pancolitis and st...

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Autores principales: Lai, Mark, He, Tony, Wright, Emily K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984941/
https://www.ncbi.nlm.nih.gov/pubmed/36879582
http://dx.doi.org/10.1159/000529671
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author Lai, Mark
He, Tony
Wright, Emily K.
author_facet Lai, Mark
He, Tony
Wright, Emily K.
author_sort Lai, Mark
collection PubMed
description Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of small to medium vessels. Gastrointestinal involvement is uncommon and is associated with higher mortality. Treatment is based on empiric evidence. In this article, we report a case of EGPA-related pancolitis and stricturing small bowel disease managed with a combination of mepolizumab and surgical resection.
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spelling pubmed-99849412023-03-05 Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response Lai, Mark He, Tony Wright, Emily K. Case Rep Gastroenterol Single Case Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of small to medium vessels. Gastrointestinal involvement is uncommon and is associated with higher mortality. Treatment is based on empiric evidence. In this article, we report a case of EGPA-related pancolitis and stricturing small bowel disease managed with a combination of mepolizumab and surgical resection. S. Karger AG 2023-03-03 /pmc/articles/PMC9984941/ /pubmed/36879582 http://dx.doi.org/10.1159/000529671 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Lai, Mark
He, Tony
Wright, Emily K.
Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response
title Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response
title_full Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response
title_fullStr Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response
title_full_unstemmed Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response
title_short Gastrointestinal Involvement of Eosinophilic Granulomatosis with Polyangiitis with Histological Evidence of Treatment Response
title_sort gastrointestinal involvement of eosinophilic granulomatosis with polyangiitis with histological evidence of treatment response
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984941/
https://www.ncbi.nlm.nih.gov/pubmed/36879582
http://dx.doi.org/10.1159/000529671
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