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Clinical Presentations of the Survivor and Non-survivor Hospitalized Patients with COVID-19 in the Golestan Province of Iran during the First Peak of the Epidemics
BACKGROUND: Considering the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, which causes coronavirus disease 2019 (COVID-19), we aimed to report the clinical features of 427 patients with COVID-19 and the outcomes after one-month admission to major teaching hospitals in the no...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Research Institute of Tuberculosis and Lung Disease
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985124/ https://www.ncbi.nlm.nih.gov/pubmed/36879730 |
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author | Abdolahi, Nafiseh Norouzi, Alireza Golsha, Roghieh Khodabakhshi, Behnaz Sohrabi, Ahmad Gharib, Mohammad Hadi Khandashpoor, Mahmoud Tavassoli, Samane Peivandi, Babak Fazel, Abdolreza Isapanah Amlashi, Fazel Livani, Somayeh Roshandel, Gholamreza Besharat, Sima Shirzad-Aski, Hesamaddin |
author_facet | Abdolahi, Nafiseh Norouzi, Alireza Golsha, Roghieh Khodabakhshi, Behnaz Sohrabi, Ahmad Gharib, Mohammad Hadi Khandashpoor, Mahmoud Tavassoli, Samane Peivandi, Babak Fazel, Abdolreza Isapanah Amlashi, Fazel Livani, Somayeh Roshandel, Gholamreza Besharat, Sima Shirzad-Aski, Hesamaddin |
author_sort | Abdolahi, Nafiseh |
collection | PubMed |
description | BACKGROUND: Considering the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, which causes coronavirus disease 2019 (COVID-19), we aimed to report the clinical features of 427 patients with COVID-19 and the outcomes after one-month admission to major teaching hospitals in the northeast of Iran. MATERIALS AND METHODS: Data of patients hospitalized with COVID-19 from 20 February 2020 to 20 April 2020 was analyzed using the R software. The cases and their outcomes were monitored up to one month following their admission. RESULTS: Among 427 patients with a median age of 53 years (50.8% male), 81 (19%) were directly admitted to the ICU ward, and 68 (16%) died during the study. The mean (SD) lengths of hospital stay were significantly higher in the non-survivors (6 (9) days) than survivors (4 (5) days) (P = 0.018). Ventilation need was reported in 67.6% of the non-survivors and 0.8% of the survivors (P < 0.001). Cough (72.8%), fever (69.3%), and dyspnea (64.0%) were the most common symptoms. There were more comorbidities in the severe cases (73.5%) and non-survivor (77.5%). Liver and kidney damage were significantly more common in non-survivors. Ninety percent of the patients had at least one abnormal chest CT scan finding, including crazy paving and consolidation patterns (27.1%), followed by the ground-glass opacity (24.7%). CONCLUSION: Results showed that the patients’ age, underlying comorbidities, levels of SpO(2), and laboratory findings at the time of admission may predict the progress of the disease and can be considered mortality-related factors. |
format | Online Article Text |
id | pubmed-9985124 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | National Research Institute of Tuberculosis and Lung Disease |
record_format | MEDLINE/PubMed |
spelling | pubmed-99851242023-03-05 Clinical Presentations of the Survivor and Non-survivor Hospitalized Patients with COVID-19 in the Golestan Province of Iran during the First Peak of the Epidemics Abdolahi, Nafiseh Norouzi, Alireza Golsha, Roghieh Khodabakhshi, Behnaz Sohrabi, Ahmad Gharib, Mohammad Hadi Khandashpoor, Mahmoud Tavassoli, Samane Peivandi, Babak Fazel, Abdolreza Isapanah Amlashi, Fazel Livani, Somayeh Roshandel, Gholamreza Besharat, Sima Shirzad-Aski, Hesamaddin Tanaffos Original Article BACKGROUND: Considering the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, which causes coronavirus disease 2019 (COVID-19), we aimed to report the clinical features of 427 patients with COVID-19 and the outcomes after one-month admission to major teaching hospitals in the northeast of Iran. MATERIALS AND METHODS: Data of patients hospitalized with COVID-19 from 20 February 2020 to 20 April 2020 was analyzed using the R software. The cases and their outcomes were monitored up to one month following their admission. RESULTS: Among 427 patients with a median age of 53 years (50.8% male), 81 (19%) were directly admitted to the ICU ward, and 68 (16%) died during the study. The mean (SD) lengths of hospital stay were significantly higher in the non-survivors (6 (9) days) than survivors (4 (5) days) (P = 0.018). Ventilation need was reported in 67.6% of the non-survivors and 0.8% of the survivors (P < 0.001). Cough (72.8%), fever (69.3%), and dyspnea (64.0%) were the most common symptoms. There were more comorbidities in the severe cases (73.5%) and non-survivor (77.5%). Liver and kidney damage were significantly more common in non-survivors. Ninety percent of the patients had at least one abnormal chest CT scan finding, including crazy paving and consolidation patterns (27.1%), followed by the ground-glass opacity (24.7%). CONCLUSION: Results showed that the patients’ age, underlying comorbidities, levels of SpO(2), and laboratory findings at the time of admission may predict the progress of the disease and can be considered mortality-related factors. National Research Institute of Tuberculosis and Lung Disease 2022-02 /pmc/articles/PMC9985124/ /pubmed/36879730 Text en Copyright© 2022 National Research Institute of Tuberculosis and Lung Disease https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Original Article Abdolahi, Nafiseh Norouzi, Alireza Golsha, Roghieh Khodabakhshi, Behnaz Sohrabi, Ahmad Gharib, Mohammad Hadi Khandashpoor, Mahmoud Tavassoli, Samane Peivandi, Babak Fazel, Abdolreza Isapanah Amlashi, Fazel Livani, Somayeh Roshandel, Gholamreza Besharat, Sima Shirzad-Aski, Hesamaddin Clinical Presentations of the Survivor and Non-survivor Hospitalized Patients with COVID-19 in the Golestan Province of Iran during the First Peak of the Epidemics |
title | Clinical Presentations of the Survivor and Non-survivor Hospitalized Patients with COVID-19 in the Golestan Province of Iran during the First Peak of the Epidemics |
title_full | Clinical Presentations of the Survivor and Non-survivor Hospitalized Patients with COVID-19 in the Golestan Province of Iran during the First Peak of the Epidemics |
title_fullStr | Clinical Presentations of the Survivor and Non-survivor Hospitalized Patients with COVID-19 in the Golestan Province of Iran during the First Peak of the Epidemics |
title_full_unstemmed | Clinical Presentations of the Survivor and Non-survivor Hospitalized Patients with COVID-19 in the Golestan Province of Iran during the First Peak of the Epidemics |
title_short | Clinical Presentations of the Survivor and Non-survivor Hospitalized Patients with COVID-19 in the Golestan Province of Iran during the First Peak of the Epidemics |
title_sort | clinical presentations of the survivor and non-survivor hospitalized patients with covid-19 in the golestan province of iran during the first peak of the epidemics |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985124/ https://www.ncbi.nlm.nih.gov/pubmed/36879730 |
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