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Epidemiology of Asthma in Patients with COVID-19: Investigation of Respiratory Allergy as a Risk Factor for COVID-19 Severity
BACKGROUND: The outcome of coronavirus disease 2019 (COVID-19) is complicated by various comorbidities; asthma, a common chronic disease, may be considered one of these conditions. This study aimed to investigate the effect of asthma as a potential comorbid condition on the COVID-19 prognosis. MATER...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Research Institute of Tuberculosis and Lung Disease
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985130/ https://www.ncbi.nlm.nih.gov/pubmed/36879737 |
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author | Moghtaderi, Mozhgan Mostafavi, Sara Hosseini Teshnizi, Saeed Mostafavi, Ali Ashraf, Mohammad Ali |
author_facet | Moghtaderi, Mozhgan Mostafavi, Sara Hosseini Teshnizi, Saeed Mostafavi, Ali Ashraf, Mohammad Ali |
author_sort | Moghtaderi, Mozhgan |
collection | PubMed |
description | BACKGROUND: The outcome of coronavirus disease 2019 (COVID-19) is complicated by various comorbidities; asthma, a common chronic disease, may be considered one of these conditions. This study aimed to investigate the effect of asthma as a potential comorbid condition on the COVID-19 prognosis. MATERIALS AND METHODS: This retrospective study included all RT-PCR confirmed COVID-19 cases recorded on the Shiraz health department's electronic database from January to May 2020. A questionnaire was designed to collect information about patients' demographics, their history of asthma and other comorbidities, and the severity of COVID-19 by contacting them by phone. RESULTS: Of 3163 COVID-19 patients, 109 (3.4%) had self-reported asthma with a mean age of 42.7 ± 19.1 years. Most patients (98%) had mild-to-moderate asthma, while 2% had severe disease. Among asthmatic patients, fourteen (12.8%) were admitted to the hospital, and five (4.6%) died. Univariate logistic regression results showed that asthma had no significant effect on hospitalization (OR 0.95, 95% CI: 0.54–1.63) and mortality (OR 1.18, 95% CI: 0.48–2.94) in patients with COVID-19. Compared living and deceased patients with COVID-19, the pooled OR was 18.2 (95% CI: 7.3–40.1) for cancer, 13.5 (95% CI: 8.2–22.5) for age 40–70 years, 3.1 (95% CI: 2–4.8) for hypertension, 3.1 (95% CI: 1.8–5.3) for cardiac disease and 2.1 (95% CI: 1.3–3.5) for diabetes mellitus. CONCLUSION: This study showed that asthma is not associated with an increased risk of hospitalization and mortality in patients with COVID-19. Further studies are needed to investigate the risk of different asthma phenotypes on the severity of COVID-19 disease. |
format | Online Article Text |
id | pubmed-9985130 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | National Research Institute of Tuberculosis and Lung Disease |
record_format | MEDLINE/PubMed |
spelling | pubmed-99851302023-03-05 Epidemiology of Asthma in Patients with COVID-19: Investigation of Respiratory Allergy as a Risk Factor for COVID-19 Severity Moghtaderi, Mozhgan Mostafavi, Sara Hosseini Teshnizi, Saeed Mostafavi, Ali Ashraf, Mohammad Ali Tanaffos Original Article BACKGROUND: The outcome of coronavirus disease 2019 (COVID-19) is complicated by various comorbidities; asthma, a common chronic disease, may be considered one of these conditions. This study aimed to investigate the effect of asthma as a potential comorbid condition on the COVID-19 prognosis. MATERIALS AND METHODS: This retrospective study included all RT-PCR confirmed COVID-19 cases recorded on the Shiraz health department's electronic database from January to May 2020. A questionnaire was designed to collect information about patients' demographics, their history of asthma and other comorbidities, and the severity of COVID-19 by contacting them by phone. RESULTS: Of 3163 COVID-19 patients, 109 (3.4%) had self-reported asthma with a mean age of 42.7 ± 19.1 years. Most patients (98%) had mild-to-moderate asthma, while 2% had severe disease. Among asthmatic patients, fourteen (12.8%) were admitted to the hospital, and five (4.6%) died. Univariate logistic regression results showed that asthma had no significant effect on hospitalization (OR 0.95, 95% CI: 0.54–1.63) and mortality (OR 1.18, 95% CI: 0.48–2.94) in patients with COVID-19. Compared living and deceased patients with COVID-19, the pooled OR was 18.2 (95% CI: 7.3–40.1) for cancer, 13.5 (95% CI: 8.2–22.5) for age 40–70 years, 3.1 (95% CI: 2–4.8) for hypertension, 3.1 (95% CI: 1.8–5.3) for cardiac disease and 2.1 (95% CI: 1.3–3.5) for diabetes mellitus. CONCLUSION: This study showed that asthma is not associated with an increased risk of hospitalization and mortality in patients with COVID-19. Further studies are needed to investigate the risk of different asthma phenotypes on the severity of COVID-19 disease. National Research Institute of Tuberculosis and Lung Disease 2022-02 /pmc/articles/PMC9985130/ /pubmed/36879737 Text en Copyright© 2022 National Research Institute of Tuberculosis and Lung Disease https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Original Article Moghtaderi, Mozhgan Mostafavi, Sara Hosseini Teshnizi, Saeed Mostafavi, Ali Ashraf, Mohammad Ali Epidemiology of Asthma in Patients with COVID-19: Investigation of Respiratory Allergy as a Risk Factor for COVID-19 Severity |
title | Epidemiology of Asthma in Patients with COVID-19: Investigation of Respiratory Allergy as a Risk Factor for COVID-19 Severity |
title_full | Epidemiology of Asthma in Patients with COVID-19: Investigation of Respiratory Allergy as a Risk Factor for COVID-19 Severity |
title_fullStr | Epidemiology of Asthma in Patients with COVID-19: Investigation of Respiratory Allergy as a Risk Factor for COVID-19 Severity |
title_full_unstemmed | Epidemiology of Asthma in Patients with COVID-19: Investigation of Respiratory Allergy as a Risk Factor for COVID-19 Severity |
title_short | Epidemiology of Asthma in Patients with COVID-19: Investigation of Respiratory Allergy as a Risk Factor for COVID-19 Severity |
title_sort | epidemiology of asthma in patients with covid-19: investigation of respiratory allergy as a risk factor for covid-19 severity |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985130/ https://www.ncbi.nlm.nih.gov/pubmed/36879737 |
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