The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis

This study was devoted to demonstrating the role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis (CP). From the results, we found that the IL-31 and IL-34 levels were significantly increased in GCF and serum of CP patients compared with healthy controls or obese patients....

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Detalles Bibliográficos
Autores principales: Luo, Ying, Ding, Yi, Chen, Yaduo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985446/
https://www.ncbi.nlm.nih.gov/pubmed/36879647
http://dx.doi.org/10.1515/biol-2022-0563
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author Luo, Ying
Ding, Yi
Chen, Yaduo
author_facet Luo, Ying
Ding, Yi
Chen, Yaduo
author_sort Luo, Ying
collection PubMed
description This study was devoted to demonstrating the role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis (CP). From the results, we found that the IL-31 and IL-34 levels were significantly increased in GCF and serum of CP patients compared with healthy controls or obese patients. Meanwhile, the area under the curve results further verified the diagnostic potential of IL-31 and IL-34 in terms of discriminating CP from obese patients at the GCF and serum levels. Finally, after 1 year of continuous treatment, we found that IL-31 and IL-34 levels were decreased in CP, suggesting their potential as biomarkers in CP treatment response. Monitoring GCF and serum levels of IL-31 and IL-34 contributed to CP detection and treatment response.
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spelling pubmed-99854462023-03-05 The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis Luo, Ying Ding, Yi Chen, Yaduo Open Life Sci Research Article This study was devoted to demonstrating the role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis (CP). From the results, we found that the IL-31 and IL-34 levels were significantly increased in GCF and serum of CP patients compared with healthy controls or obese patients. Meanwhile, the area under the curve results further verified the diagnostic potential of IL-31 and IL-34 in terms of discriminating CP from obese patients at the GCF and serum levels. Finally, after 1 year of continuous treatment, we found that IL-31 and IL-34 levels were decreased in CP, suggesting their potential as biomarkers in CP treatment response. Monitoring GCF and serum levels of IL-31 and IL-34 contributed to CP detection and treatment response. De Gruyter 2023-03-03 /pmc/articles/PMC9985446/ /pubmed/36879647 http://dx.doi.org/10.1515/biol-2022-0563 Text en © 2023 the author(s), published by De Gruyter https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License.
spellingShingle Research Article
Luo, Ying
Ding, Yi
Chen, Yaduo
The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis
title The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis
title_full The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis
title_fullStr The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis
title_full_unstemmed The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis
title_short The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis
title_sort role of il-31 and il-34 in the diagnosis and treatment of chronic periodontitis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985446/
https://www.ncbi.nlm.nih.gov/pubmed/36879647
http://dx.doi.org/10.1515/biol-2022-0563
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