A Randomised Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of Palovarotene Ophthalmic Solution

BACKGROUND AND OBJECTIVE: Palovarotene, a selective retinoic acid receptor γ agonist, is under investigation for the treatment of dry eye disease. This study aimed to determine the ocular and systemic safety, tolerability and pharmacokinetics of palovarotene ophthalmic solution (PVO-OS) in healthy a...

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Detalles Bibliográficos
Autores principales: Foster, William J., Strahs, Andrew L., Small, Kent W., Roach, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985528/
https://www.ncbi.nlm.nih.gov/pubmed/36542308
http://dx.doi.org/10.1007/s40268-022-00410-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985528/
https://www.ncbi.nlm.nih.gov/pubmed/36542308
http://dx.doi.org/10.1007/s40268-022-00410-6

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