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Recombinant Insulin-Like Growth Factor 1 Dimers: Receptor Binding Affinities and Activation Abilities

Insulin-like growth factor 1 (IGF-1) and its IGF-1 receptor (IGF-1R) belong to an important biological system that is involved in the regulation of normal growth, but that has also been recognized as playing a role in cancer. IGF-1R antagonists could be interesting for the testing of their potential...

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Detalles Bibliográficos
Autores principales:	Lin, Jingjing, Asai, Seiya, Selicharová, Irena, Mitrová, Katarína, Kaminský, Jakub, Young, Elinor, Jiráček, Jiří
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985566/ https://www.ncbi.nlm.nih.gov/pubmed/36891560 http://dx.doi.org/10.1007/s10989-023-10499-1

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