DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation

Deletion of the conserved C-terminus of the Rothmund-Thomson syndrome helicase RECQ4 is highly tumorigenic. However, while the RECQ4 N-terminus is known to facilitate DNA replication initiation, the function of its C-terminus remains unclear. Using an unbiased proteomic approach, we identify an inte...

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Detalles Bibliográficos
Autores principales: Xu, Xiaohua, Chang, Chou-Wei, Li, Min, Omabe, Kenneth, Le, Nhung, Chen, Yi-Hsuan, Liang, Feng, Liu, Yilun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985596/
https://www.ncbi.nlm.nih.gov/pubmed/36871012
http://dx.doi.org/10.1038/s41467-023-36968-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985596/
https://www.ncbi.nlm.nih.gov/pubmed/36871012
http://dx.doi.org/10.1038/s41467-023-36968-1

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